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Pneumococcal conjugate vaccine provides early protective antibody responses in children after related and unrelated allogeneic hematopoietic stem cell transplantation.
Following allogeneic hematopoietic stem cell transplantation (alloHSCT), children are at risk of life-threatening pneumococcal infections. Whereas vaccination with polysaccharide vaccines fails toExpand
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Severe isolated pulmonary Langerhans cell histiocytosis in a 6-year-old girl
Langerhans cell histiocytosis (LCH) usually affects different organs or bones. Isolated pulmonary disease is rare in childhood. We report about a 6-year-old girl with progressive pulmonaryExpand
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Immune recovery in children undergoing allogeneic stem cell transplantation: absolute CD8+CD3+ count reconstitution is associated with survival
To evaluate the correlation between kinetics of immune reconstitution and survival, we prospectively evaluated lymphocyte subsets in 32 paediatric patients undergoing allogeneic stem cellExpand
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IL-2 activated NK cell immunotherapy of three children after haploidentical stem cell transplantation.
Natural killer (NK) cells are thought to be of benefit in HLA-mismatched hematopoietic transplantation (H-SCT). Therefore, we developed a protocol for clinical-use expansion of highly enriched andExpand
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Ex vivo expansion of highly purified NK cells for immunotherapy after haploidentical stem cell transplantation in children.
BACKGROUND Allogeneic natural killer (NK) cells are known to show medium to high cytotoxic activity against HLA-nonidentical leukemia or tumor cells. For a possible benefit of post transplantExpand
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Autologous transplantation of CD133 selected hematopoietic progenitor cells in a pediatric patient with relapsed leukemia
A pediatric patient with very early meningeal relapse of his CD34+ CD133− pre-B-ALL was transplanted with 2.5 × 106/kg CD133 selected autologous progenitor cells. Enrichment of CD133+ cells resultedExpand
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Ocular symptoms in children treated with human-mouse chimeric anti-GD2 mAb ch14.18 for neuroblastoma
Abstract. Unusual ocular symptoms observed during intravenous treatment with anti-disialoganglioside antibody (Ab) in children suffering from neuroblastoma were analyzed and the results reported.Expand
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Human herpes virus‐6 DNA in cerebrospinal fluid of children undergoing therapy for acute leukaemia
alone (54Æ4%) (P < 0Æ01). Those treated with XRT + surgery (81Æ9%) had a better 5-year DSS than those treated with surgery alone (79Æ6%) or XRT alone (71Æ9%) (P < 0Æ01). However, multivariateExpand
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Novel WT1 mutation, 11p LOH, and t(7;12) (p22;q22) chromosomal translocation identified in a Wilms Tumor Case
About 5–10% of sporadic Wilms' tumors (WT) are associated with mutations in the Wilms' tumor 1 gene (WT1). More than 90% of patients with Denys‐Drash syndrome (DDS; characterized by renalExpand
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15 parameters of coagulation and fibrinolysis in children with type I diabetes mellitus (onset period).
15 parameters of coagulation and fibrinolysis were investigated in 38 children with type I diabetes mellitus without clinical signs of diabetic angiopathy. Compared to an age matched non diabeticExpand
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