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TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer
This region contains a single confirmed gene, TSLC1, whose expression is reduced or absent in A549 and several other NSCLC, hepatocellular carcinoma (HCC) and pancreatic cancer (PaC) cell lines, and is correlated with promoter methylation state in these cell lines. Expand
The complete DNA sequence of yeast chromosome III
The entire DNA sequence of chromosome III of the yeast Saccharomyces cerevisiae has been determined. This is the first complete sequence analysis of an entire chromosome from any organism. TheExpand
Direct association of TSLC1 and DAL-1, two distinct tumor suppressor proteins in lung cancer.
Restoration of TSLC1 expression strongly suppressed the metastasis of a human non-small cell lung cancer cell line, A549, from the spleen to the liver in nude mice, suggesting that TS LC1 and DAL-1 play a critical role in the same pathway involved in the suppression of lung tumor formation and metastasis. Expand
Phytase of the yeast Arxula adeninivorans
Of a number of yeasts screened for growth on phytic acid (inositol phosphates) as a sole source of carbon and phosphate, Arxula adeninivorans showed a particularly vigorous growth. This capacity wasExpand
Oncolytic virus therapy: A new era of cancer treatment at dawn
It appears that it will not be long before oncolytic virus therapy becomes a standard therapeutic option for all cancer patients, following the success in immunotherapy using immune checkpoint inhibitors. Expand
Complete DNA sequence of yeast chromosome XI
The complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome XI has been determined, and the 666,448-base-pair sequence has revealed general chromosome patterns. Expand
Linear DNA plasmids of yeasts.
  • H. Fukuhara
  • Biology, Medicine
  • FEMS microbiology letters
  • 15 August 1995
A survey of plasmids among about 1800 strains covering practically all the currently accepted species of yeast has provided a preliminary, overall view of the nature and frequency of yeast plasmid. Expand
The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis.
The nucleotide sequence of the cloned RAG5 gene indicated that it encodes a protein that is homologous to hexokinases of Saccharomyces cerevisiae, suggesting that the sugar kinase activity encoded by this gene is the only hexokinase in K. lactis. Expand
Promoter methylation of the TSLC1 gene in advanced lung tumors and various cancer cell lines
Combined analysis of promoter methylation and the allelic state in these cell lines indicated that the TSLC1 gene was often silenced not only by mono‐allelic methylation associated with loss of the other allele but also through bi‐alleic methylation. Expand
Glucose uptake in Kluyveromyces lactis: role of the HGT1 gene in glucose transport
A gene for high-affinity glucose transport, HGT1, has been isolated from the lactose-assimilating yeast Kluyveromyces lactis. Disruption strains showed much-reduced uptake of glucose at lowExpand