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The synthetic and biological studies of discorhabdins and related compounds.
Various analogues of the marine alkaloids, discorhabdins, have been synthesized. The strategy contains spirocyclization with phenyliodine(III) bis(trifluoroacetate) (PIFA), oxidative fragmentation ofExpand
Synthesis of the Marine Pyrroloiminoquinone Alkaloids, Discorhabdins
Many natural products with biologically interesting structures have been isolated from marine animals and plants such as sponges, corals, worms, etc. Some of them are discorhabdin alkaloids. TheExpand
New perspective for natural products synthesis: concise synthesis of (+)-sch 642305 by chiral auxiliary multiuse methodology.
The synthesis of (+)-Sch 642305 is an example of chiral auxiliary multiuse methodology, which shows a new perspective for the synthesis of compounds with multiple asymmetric centers. Thus, (+)-SchExpand
Absolute stereochemistry of gastric antisecretory compound P371A1 and its congener P371A2 from streptomyces species P371.
Absolute configurations of the gastric antisecretory compound P371A1 (1) and its congener P371A2 (2) from Streptomyces sp. P371 were determined on the basis of identification of the methyl glycosidesExpand
Marine pyrroloiminoquinone alkaloids.
Recent reports on the synthetic studies of marine pyrroloiminoquinone alakloids and their analogs are reviewed.
2017 #13 June
Nitrosocarbonyl mesitylene intermediate undergoes Ene reaction with the crotyl alcohol affording two regioisomeric adducts in fair yields. The sterically demanding nitrosocarbonyl mesitylene slightlyExpand
Stereochemistry of palytoxin. 4. Complete structure
Asymmetric bromolactonization catalyzed by a C3-symmetric chiral trisimidazoline.
Halolactonization is one of the fundamental transformations in synthetic organic chemistry. This reaction provides synthetically useful products, which can be employed as synthetic intermediates forExpand