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Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation
A very strong direct relationship is reported between the amount of cortical reorganization and the magnitude of phantom limb pain (but not non-painful phantom phenomena) experienced after arm amputation, indicating that phantom-limb pain is related to, and may be a consequence of, plastic changes in primary somatosensory cortex.
A spelling device for the paralysed
A new means of communication for the completely paralysed that uses slow cortical potentials of the electro-encephalogram to drive an electronic spelling device is developed.
Deficient fear conditioning in psychopathy: a functional magnetic resonance imaging study.
This dissociation of emotional and cognitive processing may be the neural basis of the lack of anticipation of aversive events in criminal psychopaths.
Activation of Cortical and Cerebellar Motor Areas during Executed and Imagined Hand Movements: An fMRI Study
The results of cortical activity support the hypothesis that motor imagery and motor performance possess similar neural substrates as well as the assumption that the posterior cerebellum is involved in the inhibition of movement execution during imagination.
Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Standardized protocol and reference values
Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter
Healthy carriers of the SLC6A4 short (s) allele showed stronger activation of the amygdala on functional magnetic resonance imaging, which may contribute to the abnormally high activity in the amygdala and medial prefrontal cortex seen in major depression.
Phantom-limb pain: characteristics, causes, and treatment
- H. Flor
- Medicine, PsychologyThe Lancet Neurology
- 1 July 2002
Phantom limb pain: a case of maladaptive CNS plasticity?
Evidence for putative pathophysiological mechanisms with an emphasis on central, and in particular cortical, changes is discussed and suggestions for innovative interventions aimed at alleviating phantom pain are derived.
Catechol-O-Methyltransferase val158met Genotype Affects Processing of Emotional Stimuli in the Amygdala and Prefrontal Cortex
It is concluded that genetic variations can account for a substantial part of interindividual variance in task-related brain activation and that increased limbic and prefrontal activation elicited by unpleasant stimuli in subjects with more met158 alleles might contribute to the observed lower emotional resilience against negative mood states.