Rat P45017α from Testis: Characterization of a Full-Length cDNA Encoding a Unique Steroid Hydroxylase Capable of Catalyzing Both Δ4- and Δ5-Steroid-17,20-Lyase Reactions
- H. Fevold, M. Lorence, J. Mason
- Biology
- 1 June 1989
A cDNA clone encoding the complete rat 17α-hydroxylase (P45017α) from testis has been identified and sequenced. The deduced amino acid sequence is found to have 69% similarity with human P45017α, 64%…
PREPARATION OF HUMAN GROWTH HORMONE BY GEL FILTRATION.
- P. Roos, H. Fevold, C. Gemzell
- Biology, MedicineBiochimica et Biophysica Acta
- 1963
Regulation of the adrenal and gonadal microsomal mixed function oxygenases of steroid hormone biosynthesis.
- H. Fevold
- Biology, ChemistryAnnual Review of Physiology
- 1983
The control of the adrenal and gonadal microsomal roixed function oxygenase enzymes that catalyze the reactions leading to the major reactions in steroidogenesis are reviewed.
Rat P450(17 alpha) from testis: characterization of a full-length cDNA encoding a unique steroid hydroxylase capable of catalyzing both delta 4- and delta 5-steroid-17,20-lyase reactions.
- H. Fevold, M. Lorence, J. Mason
- BiologyMolecular Endocrinology
- 1989
A cDNA clone encoding the complete rat 17 alpha-hydroxylase (P450(17 alpha] from testis has been identified and sequenced. The deduced amino acid sequence is found to have 69% similarity with human…
ACTH-induced increases in rabbit adrenal immunoreactive P-450(17 alpha) and P-450(21).
- M. Chouinard, H. Fevold
- BiologyMolecular and Cellular Endocrinology
- 1990
It was found that the total and specific contents of rabbit adrenal immunoreactive P-450(17 alpha) were increased 6- to 8-fold and 4-fold, respectively, after ACTH stimulation, whether the detection system was 125I-labeled protein A or an alkaline phosphatase-conjugated second antibody.
Factors affecting the adrenocorticotropic hormone stimulation of rabbit adrenal 17alpha-hydroxylase activity.
- H. Fevold, H. B. Drummond
- Biology, MedicineBiochimica et Biophysica Acta
- 30 June 1973
Regulation of the Adrenal Cortex Secretory Pattern by Adrenocorticotropin
- H. Fevold
- Biology, MedicineScience
- 30 June 1967
Adrenal gland homogenates from rabbits stimulated for 28 days with adrenocorticotropin have been shown to synthesize cortisol, and when Δ5-pregnenolone substrate was used the specific activity of the isolated cortisol was four times as great as when progesterone was used.
ACTH-stimulated rabbit adrenal 17α-hydroxylase. Kinetic properties and a comparison with those of 3β-hydroxysteroid dehydrogenase
- H. Fevold, P. L. Wilson, S. Slanina
- Biology, Medicine
- 1 November 1978
The enzyme specificity of ACTH stimulation of rabbit adrenal microsomal 17 alpha-hydroxylase activity.
- S. Slanina, H. Fevold
- Biology, MedicineJournal of Steroid Biochemistry
- 1982
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