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Leptin promotes metastasis by inducing an epithelial-mesenchymal transition in A549 lung cancer cells.
Leptin, an adipocyte-derived cytokine associated with obesity, has been reported to participate in carcinogenesis. Epithelial-mesenchymal transition (EMT) is also considered as a key event in tumor… Expand
Artesunate down-regulates immunosuppression from colorectal cancer Colon26 and RKO cells in vitro by decreasing transforming growth factor β1 and interleukin-10.
Immunosuppression is the main source of ineffective treatment on tumor, and the study aimed to investigate the effect of artesunate on tumor immunosuppression. Supernatants of re-cultivated murine… Expand
Hypoxia-induced autophagy as an additional mechanism in human osteosarcoma radioresistance
Osteosarcoma (OS) responds poorly to radiotherapy, but the mechanism is unclear. We found OS tumor tissues expressed high level of protein HIF-1α, a common biological marker indicative of hypoxia. It… Expand
Bevacizumab Attenuates Hepatic Fibrosis in Rats by Inhibiting Activation of Hepatic Stellate Cells
Angiogenesis is a fundamental part of the response to tissue injury, which is involved in the development of hepatic fibrosis. Vascular endothelial growth factor plays an important role in… Expand
The expression of SIRT1 regulates the metastaticplasticity of chondrosarcoma cells by inducing epithelial-mesenchymal transition
- H. Feng, J. Wang, Jianfa Xu, Congcong Xie, F. Gao, Z. Li
- Biology, Medicine
- Scientific reports
- 23 January 2017
SIRT1 belongs to the mammalian sirtuin family and plays an important role in deacetylating histone and nonhistone proteins. It is reported that SIRT1 is associated with tumor metastasis in several… Expand
Resveratrol inhibits hypoxia-induced glioma cell migration and invasion by the p-STAT3/miR-34a axis.
Hypoxia promotes aggressiveness, angiogenesis and resistance in glioma. It has been reported that resveratrol has strong anti-tumor ability and can inhibit migration and invasion of varieties of… Expand
Mechanism of miR-143-3p inhibiting proliferation, migration and invasion of osteosarcoma cells by targeting MAPK7
- Yu Hou, H. Feng, +5 authors Z. Liang
- Materials Science, Medicine
- Artificial cells, nanomedicine, and biotechnology
- 24 May 2019
Abstract Objective: To investigate the effects of miR-143-3p and MAPK7 on the proliferation, migration, and invasion of U2OS human osteosarcoma (OS) cells. Methods: The expression of miR-143-3p and… Expand
C3 Vertebral Metastases From Tongue Adenoid Cystic Carcinoma
AbstractWe report a rare case involving a patient with C3 vertebral body metastasis secondary to adenoid cystic carcinoma of the tongue.Five years after local resection of the primary tumor, magnetic… Expand
Percutaneous femoroplasty for the treatment of proximal femoral metastases.
- H. Feng, J. Feng, +6 authors Y. Zhang
- European journal of surgical oncology : the…
- 1 April 2014
PURPOSE To investigate the clinical value of percutaneous perfusion of bone cement as a treatment for proximal femoral metastases. METHODS Twenty-one patients with 23 lesion sites of proximal… Expand
CT-Guided Percutaneous Femoroplasty (PFP) for the Treatment of Proximal Femoral Metastases.
BACKGROUND The spine, pelvis, skull, and femur are the most common sites of bone metastases, and pain is the main symptom of metastatic tumors. Percutaneous femoroplasty (PFP) is becoming… Expand