Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- D. Klionsky, K. Abdelmohsen, S. Zughaier
- BiologyAutophagy
- 18 April 2012
There continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes, so it is important to update guidelines for monitoring autophagic activity in different organisms.
NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage
- Qingyi Ma, Sheng Chen, Qin Hu, H. Feng, John H. Zhang, Jiping Tang
- Biology, MedicineAnnals of Neurology
- 1 February 2014
This work investigated whether NLRP3 knockdown decreases neutrophil infiltration, reduces brain edema, and improves neurological function in an intracerebral hemorrhage mouse model, and determined whether mitochondrial reactive oxygen species (ROS) governed by mitochondrial permeability transition pores (mPTPs) would triggerNLRP3 inflammasome activation following ICH.
Controversies and evolving new mechanisms in subarachnoid hemorrhage
- Sheng Chen, H. Feng, John H. Zhang
- MedicineProgress in neurobiology
- 1 April 2014
Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury
- Hai-tao Zhu, Chen Bian, Jiangkai Lin
- BiologyJournal of Neuroinflammation
- 27 March 2014
The results suggest that post-injury, curcumin administration may improve patient outcome by reducing acute activation of microglia/macrophages and neuronal apoptosis through a mechanism involving the TLR4/MyD88/NF-κB signaling pathway in micro glia/ Macrophages in TBI.
Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial
- D. Hanley, R. Thompson, A. Zomorodi
- MedicineThe Lancet
- 9 March 2019
The Injury and Therapy of Reactive Oxygen Species in Intracerebral Hemorrhage Looking at Mitochondria
- Jie Qu, Weixiang Chen, Rong Hu, H. Feng
- Biology, MedicineOxidative Medicine and Cellular Longevity
- 12 May 2016
The mitochondrion may be a significant target for elucidating the problem of ROS in ICH and the drugs aiming to decrease ROS after ICH, and it is found that mitochondria are key players in all of these aspects.
Glioma-initiating cells: A predominant role in microglia/macrophages tropism to glioma
- Liang Yi, Hualiang Xiao, H. Feng
- Biology, MedicineJournal of Neuroimmunology
- 1 March 2011
Glial scar and neuroregeneration: histological, functional, and magnetic resonance imaging analysis in chronic spinal cord injury.
- Rong Hu, Jian-jun Zhou, H. Feng
- Biology, MedicineJournal of Neurosurgery : Spine
- 1 August 2010
A critical time window of postinjury recovery and a detailed spatial orientation of glial scar are revealed, which would provide an important basis for the development of therapeutic strategy for glial Scar ablation.
Curcumin inhibits microglia inflammation and confers neuroprotection in intracerebral hemorrhage.
- Zhao Yang, Tianzhi Zhao, Yong-jie Zou, John H. Zhang, H. Feng
- BiologyImmunology Letters
- 1 July 2014
Cerebral paragonimiasis: A retrospective analysis of 89 cases
- Jing-yu Chen, Zhi Chen, H. Feng
- MedicineClinical neurology and neurosurgery (Dutch…
- 1 May 2013
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