Author pages are created from data sourced from our academic publisher partnerships and public sources.
Ultrastructural differences in efferent ducts and several regions of the epididymis of the hamster.
The ultrastructure of the hamster efferent ducts and epididymis was studied and the results were correlated with previously published data on the composition of luminal fluid obtained by… Expand
Cell proliferation, DNA repair, and p53 function are not required for programmed death of prostatic glandular cells induced by androgen ablation.
- R. Berges, Y. Furuya, L. Remington, H. English, T. Jacks, J. Isaacs
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 1 October 1993
Androgen ablation induces programmed death of androgen-dependent prostatic glandular cells, resulting in fragmentation of their genomic DNA and the cells themselves into apoptotic bodies. Twenty… Expand
Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.
To study the mechanism of regression of human prostatic cancer following androgen ablation, the androgen-responsive PC-82 human prostatic adenocarcinoma xenograft was used as a model system.… Expand
Relationship between DNA fragmentation and apoptosis in the programmed cell death in the rat prostate following castration
Previous studies have demonstrated that the rapid involution of the rat ventral prostate following castration involves the death of the androgen‐dependent epithelial cells present within the gland… Expand
Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine
- M. Dolan, G. L. Larkin, H. English, A. Pegg
- Biology, Medicine
- Cancer Chemotherapy and Pharmacology
SummaryWe have previously shown that exposure of cells in culture to O6-methylguanine significantly reduces their level of the repair protein, O6-alkylguanine-DNA-alkyltransferase (AGT), thus… Expand
Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation.
To study the mechanism of regression of human mammary cancer following estrogen ablation, estrogen-responsive MCF-7 human mammary adenocarcinoma cells were inoculated into ovariectomized female nude… Expand
Activation of a Ca2+−Mg2+‐dependent endonuclease as an early event in castration‐induced prostatic cell death
Previous studies have demonstrated that castration‐induced androgen withdrawal results in the fragmentation of prostatic DNA into nucleosomal oligomers, and this process comprises an early event in… Expand
Androgen regulation of programmed death of normal and malignant prostatic cells.
- J. Isaacs, P. Lundmo, R. Berges, P. Martikainen, N. Kyprianou, H. English
- Biology, Medicine
- Journal of andrology
- 12 November 1992
Androgen-dependent normal prostatic glandular cells and androgen-dependent prostatic cancer cells can be induced to undergo cell death after androgen ablation. This death does not require the cells… Expand
Proliferative response of the Dunning R3327H experimental model of prostatic adenocarcinoma to conditions of androgen depletion and repletion.
Administration of androgen to the castrate rat elicits a pronounced wave of proliferative activity in the ventral prostate gland. We wished to determine if this phenomenon could also be demonstrated… Expand
Comparison of cemented vs uncemented acetabular component positioning using an imageless navigation system.
- Mayur Chawda, P. Hucker, Sarah L. Whitehouse, Ross W. Crawford, H. English, William J. Donnelly
- The Journal of arthroplasty
- 1 December 2009
Hip navigation was used as an assessment tool to compare ability to reproduce trial and definitive acetabular placement in total hip arthroplasty, using cemented and uncemented components. We… Expand