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The Pharmacology of Lysergic Acid Diethylamide: A Review
TLDR
There is new interest in LSD as an experimental tool for elucidating neural mechanisms of (states of) consciousness and there are recently discovered treatment options with LSD in cluster headache and with the terminally ill. Expand
Psychotomimesis mediated by kappa opiate receptors
TLDR
In male subjects, the opiate-active (-)-isomer, but not the (+)- isomer, elicited dose-dependent dysphoric and psychotomimetic effects that were antagonized by naloxone, implying the existence of opposed opioid systems affecting emotional and perceptual experiences. Expand
Discrepant target detection and action monitoring in obsessive–compulsive disorder
TLDR
The data provide partial support for the hypothesis of a hyperactive neural network in OCD, and suggest that the disorder must involve pathophysiological processes that are presumably related to other aspects of its complex and heterogeneous clinical hallmarks. Expand
The pharmacology of psilocybin
TLDR
All the available pharmacological data about psilocybin are presented and its still growing capacity for abuse and the widely dispersed data are presented. Expand
Comorbidity of alcohol and substance dependence with attention-deficit/hyperactivity disorder (ADHD).
TLDR
It is revealed that habit-forming illnesses can be associated with a high comorbidity with ADHD, expressed in the form of alcohol abuse and also in consumption of illegal drugs. Expand
Elevated endogenous cannabinoids in schizophrenia.
TLDR
Elevated anandamide and palmitylethanolamide levels in cerebrospinal fluid of schizophrenic patients may reflect an imbalance in endogenous cannabinoid signaling, which may contribute to the pathogenesis of schizophrenia. Expand
Towards a Cannabinoid Hypothesis of Schizophrenia: Cognitive Impairments Due to Dysregulation of the Endogenous Cannabinoid System
TLDR
Neuropsychological results (three-dimensional inversion illusion) in delta 9-tetrahydrocannabinol-intoxicated normal volunteers exhibit strong similarities with data acquired from patients suffering from productive schizophrenic psychoses, regarding disturbances in internal regulation of perceptual processes. Expand
Genuine and drug-induced synesthesia: A comparison
TLDR
A major implication of the phenomenological comparison in regard to the etiological models is that genuine and acquired synesthesias point to morphological substrates, while drug-induced synesthesia appears to be based on functional changes of brain activity. Expand
Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence.
TLDR
It is shown that recent studies provided supporting evidence that PTSD patients may be able to cope with their symptoms by using cannabis products and it is concluded that further studies are warranted in order to evaluate the therapeutic potential of cannabinoids in PTSD. Expand
High frequency repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex in schizophrenic patients
TLDR
The Brief Psychiatric Rating Scale decreased under active rTMS (p < 0.05), whereas depressive symptoms (BDI) and anxiety (STAI) did not change significantly, suggesting prefrontal rT MS might be effective in the non-pharmacological treatment of psychotic patients. Expand
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