Sulfamylurea hypoglycemic agents. 6. High-potency derivatives.
- R. Sarges, D. E. Kuhla, H. E. Wiedermann, D. Mayhew
- ChemistryJournal of Medicinal Chemistry
- 1 May 1976
Synthetic methods for a series of novel sulfamylurea derivatives have been developed and one of these compounds was found to be well tolerated in man and it displayed a very short plasma half-life.
SULFAMYLUREA HYPOGLYCEMIC AGENTS. 6. HIGH-POTENCY DERIVATIVES
- R. Sarges, D. E. Kuhla, H. E. Wiedermann, D. Mayhew
- Chemistry
- 5 October 1976
United States Patent to Wiedermann 54 4-2-( 1 , 3-DIALKYL-1 , 2 , 3 , 4-TETRA HYDROPYRIMIDINE-2 , 4-DIONE-5-CAR BOXAMIDO ) ETHYL-1-PIPERIDINE SULFONAMIDE 75 )
- H. E. Wiedermann
- Chemistry
- 2017
57 ABSTRACT A series of novel 1-piperidinesulfonylurea compounds derived from a pyrimidine monocarboxylic acid have been prepared by reacting an appropriate sulfamide with an organic isocyanate or a…