• Publications
  • Influence
Practice guidelines for the management of infectious diarrhea.
The widening array of recognized enteric pathogens and the increasing demand for cost-containment sharpen the need for careful clinical and public health guidelines based on the best evidenceExpand
The infectivity of Cryptosporidium parvum in healthy volunteers.
BACKGROUND Small numbers of Cryptosporidium parvum oocysts can contaminate even treated drinking water, and ingestion of oocysts can cause diarrheal disease in normal as well as immunocompromisedExpand
Economic healthcare costs of Clostridium difficile infection: a systematic review.
Clostridium difficile infection (CDI) is the leading cause of infectious diarrhoea in hospitalised patients. CDI increases patient healthcare costs due to extended hospitalisation,Expand
Global etiology of travelers' diarrhea: systematic review from 1973 to the present.
Fifty-one published studies of travelers' diarrhea (TD) were examined to look for regional differences in pathogens identified. Enterotoxigenic E. coli was detected in 1,678/5,518 (30.4%) of TD casesExpand
Virulence of three distinct Cryptosporidium parvum isolates for healthy adults.
The infectivity of three Cryptosporidium parvum isolates (Iowa [calf], UCP [calf], and TAMU [horse]) of the C genotype was investigated in healthy adults. After exposure, volunteers recorded theExpand
Biological Properties of Norwalk Agent of Acute Infectious Nonbacterial Gastroenteritis
Summary Acute infectious nonbacterial gastroenteritis was induced in adult volunteers through three serial passages by oral administration of bacteria-free stool filtrates. This suggested that aExpand
Traveler's diarrhea: a clinical review.
IMPORTANCE Acute diarrhea is the most common illness that affects travelers to low-income regions of the world. Although improved hygiene has reduced the risk of traveler's diarrhea in manyExpand
Pathogenesis of Escherichia coli diarrhea.
Abstract Two Escherichia coli strains isolated in Vietnam from American soldiers with diarrhea and acute "colitis" were examined for virulence in both in vitro and in vivo experimental models. Thei...
Meta-analysis to assess risk factors for recurrent Clostridium difficile infection.
SUMMARY Clostridium difficile infection (CDI) is the most common cause of hospital-acquired diarrhoea. It is estimated that 15-20% of patients experience recurrence of CDI. A limited number ofExpand