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Epizootic of adenovirus infection in American black bears.
Overview of currently approved veterinary vaccine potency testing methods and methods in development that do not require animal use
- H. Draayer
Veterinary vaccines must be safe, pure, potent, and effective. Potency tests help ensure that each consistently manufactured batch of vaccine provides a level of protection as determined in the… Expand
Insecticides, polychlorinate biphenyls and metals in African lake ecosystems. II. Lake McIlwaine, Rhodesia.
Insecticides, polychlorinated biphenyls and metals in african lake ecosystems. II. Lake Mcllwaine, Rhodesia
In an effort to examine biological accumulation of pollutants in an African lake ecosystem samples of water, bottom sediment, oligochaetes, benthic insects, three species of fish, and a fish eating… Expand
Non-animal replacement methods for veterinary vaccine potency testing: state of the science and future directions
Abstract NICEATM and ICCVAM convened an international workshop to review the state of the science of human and veterinary vaccine potency and safety testing methods and to identify opportunities… Expand
Characterization of canine adenovirus type 1 isolated from American black bears.
- C. Whetstone, H. Draayer, J. Collins
- Biology, Medicine
- American journal of veterinary research
- 1 June 1988
Viruses recovered from tissues taken at necropsy from American black bears were examined by use of immunofluorescence with polyclonal and monoclonal antibodies, virus neutralization with monoclonal… Expand
Alternative methods and strategies to reduce, refine, and replace animal use for veterinary vaccine post-licensing safety testing: state of the science and future directions
NICEATM and ICCVAM convened an international workshop to review the state of the science of human and veterinary vaccine potency and safety testing methods and to identify opportunities to advance… Expand
Improving animal welfare and reducing animal use for veterinary vaccine potency testing: state of the science and future directions
Abstract Veterinary vaccines contribute to improved human and animal health and welfare by preventing diseases and deaths caused by a wide range of infectious agents. However, testing necessary to… Expand
Autogenous vaccines: determining product need and antigen selection, production and testing considerations.
- H. Draayer
- Developments in biologicals
It is estimated that in the 12-month period from May 1999--April 2000 approximately $16.06 million in swine autogenous vaccines were sold in the United States. Swine influenza and PRRS vaccines… Expand
An international collaborative study on a method for determination of formaldehyde in veterinary vaccines.
An international collaborative study of a quantitative colorimetric method for determination of formaldehyde in veterinary vaccines was conducted on a series of replicate, blinded veterinary vaccine… Expand