H. Doorne

Publications39
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Citations355
Highly Influential Citations3
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Microbiological stability of tablets stored under tropical conditions
Saponin, an inhibitory agent of carbon dioxide production by white cells: its use in the microbiologic examination of blood components in an automated bacterial culture system
TLDR
Saponin at a concentration of 0.5 percent is a valuable additive to BacT/Alert culture media because it prevents false‐positive results in the examination of white cell‐rich blood components.
PSARP, a programmable signal and response processor
TLDR
This paper gives an outline of the principles of a flexible and programmable system which meets the requirements of a considerable number of variables.
Skin irritation caused by transdermal drug delivery systems during long‐term (5 days) application
TLDR
The results showed that sweat accumulation contributed more to the skin irritation than the bacterial overgrowth, and the incorporation of hydrogels in the transdermal delivery system may help to reduce skin irritation by absorbing water.
ACTIVITY OF GENTIAN VIOLET AND BRILLIANT GREEN AGAINST SOME MICROORGANISMS ASSOCIATED WITH SKIN INFECTIONS
TLDR
Gentian violet was found to be more active than brilliant green at pH 7.4, particularly against Pseudomonas aeruginosa, and an aqueous solution of gentian violet 0.5% turned out to be an adequate topical anti‐infective drug.
Native starch in tablet formulations: Properties on compaction
TLDR
Rice starch showed much better compactibility as compared to maize, potato and tapioca starch, and its binding capacity proved to be almost insensitive to mixing with magnesium stearate, in contrast to the dramatic decrease in crushing strength of potato starch tablets containing the lubricant.
β-Cyclodextrin as an excipient in solid oral dosage forms: in vitro and in vivo evaluation of spray-dried diazepam-β-cyclodextrin products
Bacteriostatic activity of some coumarin derivatives
Formation arid antimicrobial activity of complexes of β-cyclodextrin and some antimycotic imidazole derivatives
TLDR
The antimycotic drugs were more readily released from topical preparations containing \-cyclodextrin than from the same vehicles without β-cyclodesxtrin, and the solubility of all drugs was increased in the presence of β- cyclodextrine.
Stability and in vitro activity of nystatin and its γ-cyclodextrin complex against Candida albicans
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