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The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium
The PAR-1 kinase plays a conserved role in cell polarity in C. elegans, Drosophila and mammals. We have investigated the role of PAR-1 in epithelial polarity by generating null mutant clones in theExpand
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Drosophila Anterior-Posterior Polarity Requires Actin-Dependent PAR-1 Recruitment to the Oocyte Posterior
The Drosophila anterior-posterior axis is established at stage 7 of oogenesis when the posterior follicle cells signal to polarize the oocyte microtubule cytoskeleton. This requires the conservedExpand
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Bazooka is required for polarisation of the Drosophila anterior-posterior axis
The Drosophila anterior-posterior (AP) axis is determined by the polarisation of the stage 9 oocyte and the subsequent localisation of bicoid and oskar mRNAs to opposite poles of the cell. OocyteExpand
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Cortical microtubule nucleation can organise the cytoskeleton of Drosophila oocytes to define the anteroposterior axis
Many cells contain non-centrosomal arrays of microtubules (MTs), but the assembly, organisation and function of these arrays are poorly understood. We present the first theoretical model for theExpand
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Differential expression of the Drosophila zinc finger gene jim in the follicular epithelium
The Drosophila gene jim was identified by an enhancer trap line showing asymmetric dorso-ventral expression in the follicular epithelium. It gives rise to the jim-1 and jim-2 transcripts that containExpand
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Repair of oxidative DNA damage in Drosophila melanogaster: identification and characterization of dOgg1, a second DNA glycosylase activity for 8-hydroxyguanine and formamidopyrimidines.
In Drosophila, the S3 ribosomal protein has been shown to act as a DNA glycosylase/AP lyase capable of releasing 8-hydroxyguanine (8-OH-Gua) in damaged DNA. Here we describe a second DrosophilaExpand
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Etude structurale et fonctionnelle du locus jules et jim de drosophila melanogaster
L'etude de la lignee piege a enhancer ovk qui presente une insertion du transposon plac ; w dans la region 79f1-2 du genome, a permis d'identifier un nouveau gene chez la drosophile, nomme jim,Expand
Consultation en équilibre alimentaire en santé au travail
Les desequilibres alimentaires, le surpoids et l’obesite sont des problemes de sante publique a l’origine de nombreuses pathologies et ne cessent d’augmenter depuis 20 ans en France. L’action deExpand