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A Central Role for P48/45 in Malaria Parasite Male Gamete Fertility
Fertilization and zygote development are obligate features of the malaria parasite life cycle and occur during parasite transmission to mosquitoes. The surface protein PFS48/45 is expressed by maleExpand
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Characterization of the tubulin-tyrosine ligase
The sequence of tubulin-tyrosine ligase (TTL), the enzyme catalyzing the ATP-dependent posttranslational addition of a tyrosine to the carboxyterminal end of detyrosinated alpha-tubulin, has beenExpand
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Eight genes and alternative RNA processing pathways generate an unexpectedly large diversity of cytoplasmic intermediate filament proteins in the nematode Caenorhabditis elegans.
Cytoplasmic intermediate filament (IF) proteins of Caenorhabditis elegans are encoded by a dispersed multigene family comprising at least eight genes which map to three linkage groups. Exon sequencesExpand
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Structure of an invertebrate gene encoding cytoplasmic intermediate filament (IF) proteins: implications for the origin and the diversification of IF proteins.
The structure of the single gene encoding the cytoplasmic intermediate filament (IF) proteins in non‐neuronal cells of the gastropod Helix aspersa is described. Genomic and cDNA sequences show thatExpand
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Lenticular intermediate-sized filaments: biosynthesis and interaction with plasma membrane.
Electron microscopical features of the lens fiber plasma membrane-cytoskeleton complex are suggestive of an intimate association between the intermediate-sized filaments (IF) and the lipid bilayer.Expand
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epsilon-Crystallin, a novel avian and reptilian eye lens protein.
Gel filtration of Peking duck eye lens proteins reveals a component eluting just behind delta-crystallin and comprising approximately 10% of the total soluble protein. The native Mr of thisExpand
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The genes coding for the cytoskeletal proteins actin and vimentin in warm‐blooded vertebrates.
Recombinant plasmids were made containing cDNAs synthesized on hamster mRNAs coding for cytoskeletal (beta‐ or gamma‐) actins and for vimentin. Hybridization of the actin probe on restriction digestsExpand
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Amino acid sequences and homopolymer‐forming ability of the intermediate filament proteins from an invertebrate epithelium.
Intermediate filaments (IF) isolated from the oesophagus epithelium of the snail Helix pomatia contain two polypeptides of mol. wt 66,000 (A) and 52,000 (B), which we have now characterized by inExpand
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SV40-transformed hamster lens epithelial cells: a novel system for the isolation of cytoskeletal messenger RNAs and their translation products.
Epithelial cells from Syrian hamster lens were cultured and transformed by Simian Virus 40 (SV40). This cell line can be brought into suspension culture and then grows very efficiently. TheExpand
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Developmentally regulated expression of pfs16, a marker for sexual differentiation of the human malaria parasite Plasmodium falciparum.
Sexual differentiation is essential for the transmission of Plasmodium to mosquitoes and therefore, for the spread of malaria. The molecular mechanisms underlying sexual differentiation are poorlyExpand
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