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Insensitivity to future consequences following damage to human prefrontal cortex
Following damage to the ventromedial prefrontal cortex, humans develop a defect in real-life decision-making, which contrasts with otherwise normal intellectual functions. Currently, there is noExpand
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Impairment of social and moral behavior related to early damage in human prefrontal cortex
The long-term consequences of early prefrontal cortex lesions occurring before 16 months were investigated in two adults. As is the case when such damage occurs in adulthood, the two early-onsetExpand
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Damage to the Insula Disrupts Addiction to Cigarette Smoking
A number of brain systems have been implicated in addictive behavior, but none have yet been shown to be necessary for maintaining the addiction to cigarette smoking. We found that smokers with brainExpand
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The return of Phineas Gage: clues about the brain from the skull of a famous patient.
When the landmark patient Phineas Gage died in 1861, no autopsy was performed, but his skull was later recovered. The brain lesion that caused the profound personality changes for which his caseExpand
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Investment Behavior and the Negative Side of Emotion
Can dysfunction in neural systems subserving emotion lead, under certain circumstances, to more advantageous decisions? To answer this question, we investigated how normal participants, patients withExpand
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A role for left temporal pole in the retrieval of words for unique entities
Both lesion and functional imaging studies have implicated sectors of high‐order association cortices of the left temporal lobe in the retrieval of words for objects belonging to varied conceptualExpand
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Role of the Amygdala in Decision‐Making
Abstract: The somatic marker hypothesis proposes that both the amygdala and the orbitofrontal cortex are parts of a neural circuit critical for judgment and decision‐making. Although both structuresExpand
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Brainvox: An Interactive, Multimodal Visualization and Analysis System for Neuroanatomical Imaging
A study of cognition emerging from a neurobiological perspective, as opposed to a purely computational or psychological perspective, begins with observations of the human brain in normal and pathological states and is furthered by the investigation of hypotheses which are articulated using neuroanatomical nomenclature. Expand
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Neuroanatomical correlates of electrodermal skin conductance responses.
We studied the electrodermal skin conductance responses (SCRs) of 36 subjects with well-characterized lesions in various regions of the cerebral hemispheres. Several lesion loci were consistentlyExpand
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Neural Correlates of Naming Actions and of Naming Spatial Relations
Ina [(15)O] water PET experiment, 10 normal subjects retrieved words denoting actions (performed with or without an implement), and another 10 normal subjects retrieved words denoting the spatialExpand
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