H. Damasio

Publications284
h-index98
Citations59,258
Highly Influential Citations2,972
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Insensitivity to future consequences following damage to human prefrontal cortex
Deciding Advantageously Before Knowing the Advantageous Strategy
TLDR
The results suggest that, in normal individuals, nonconscious biases guide behavior before conscious knowledge does, and without the help of such biases, overt knowledge may be insufficient to ensure advantageous behavior.
Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions.
TLDR
Patients with VM lesions are insensitive to future consequences, positive or negative, and are primarily guided by immediate prospects, according to this study's designs of a variant of the original gambling task.
Emotion, decision making and the orbitofrontal cortex.
TLDR
The somatic marker hypothesis provides a systems-level neuroanatomical and cognitive framework for decisionMaking and the influence on it by emotion and the relationship between emotion, decision making and other cognitive functions of the frontal lobe, namely working memory is reviewed.
Different Contributions of the Human Amygdala and Ventromedial Prefrontal Cortex to Decision-Making
TLDR
The results suggest that amygdala damage is associated with impairment in decision-making and that the roles played by the amygdala and VMF in decision -making are different.
Subcortical and cortical brain activity during the feeling of self-generated emotions
TLDR
The hypothesis that the process of feeling emotions requires the participation of brain regions that are involved in the mapping and/or regulation of internal organism states is tested, indicating the close relationship between emotion and homeostasis.
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE
TLDR
This work conquers the constrained surface registration problem by changing the Riemannian metric on the target surface to a hyperbolic metric so that the harmonic mapping is guaranteed to be a diffeomorphism under landmark constraints.
Failure to respond autonomically to anticipated future outcomes following damage to prefrontal cortex.
TLDR
A physiological correlate for the defect of prefrontal damage is identified and its possible significance is discussed, compatible with the idea that these patients fail to activate biasing signals that would serve as value markers in the distinction between choices with good or bad future outcomes.
Dissociation Of Working Memory from Decision Making within the Human Prefrontal Cortex
TLDR
A cognitive and anatomic double dissociation between deficits in decision making (anterior VM) and working memory (right DL/M) is revealed, the first direct evidence of such effects in humans using the lesion method and underscores the special importance of the VM prefrontal region in decisionMaking, independent of a direct role in working memory.
Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences
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