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Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction.
- N. W. Kam, M. O'connell, J. Wisdom, H. Dai
- Biology, ChemistryProceedings of the National Academy of Sciences…
- 16 August 2005
It is shown here that the strong optical absorbance of single-walled carbon nanotubes (SWNTs) in this special spectral window, an intrinsic property of SWNTs, can be used for optical stimulation of nanot tubes inside living cells to afford multifunctional nanotube biological transporters.
Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery.
This work introduces the concept of "functionalization partitioning" of SWNTs, i.e., imparting multiple chemical species, such as PEG, drugs, and fluorescent tags, with different functionalities onto the surface of the same nanotube, which should open up new opportunities in chemical, biological, and medical applications of novel nanomaterials.
In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice.
It is found that SWNTs that are functionalized with phospholipids bearing polyethylene-glycol (PEG) are surprisingly stable in vivo, and a high tumour accumulation is attributed to the multivalent effect of theSWNTs.
Noncovalent sidewall functionalization of single-walled carbon nanotubes for protein immobilization.
- R. J. Chen, Y. Zhang, D. Wang, H. Dai
- ChemistryJournal of the American Chemical Society
- 18 April 2001
Single-walled carbon nanotubes are molecular wires that exhibit interesting structural, mechanical, electrical, and electromechanical properties that make for an ideal miniaturized sensor.
Room-temperature all-semiconducting sub-10-nm graphene nanoribbon field-effect transistors.
- Xinran S. Wang, Y. Ouyang, Xiaolin Li, Hailiang Wang, Jing Guo, H. Dai
- PhysicsPhysical review letters
- 24 March 2008
The sub-10 nm GNRFETs are comparable to small diameter carbon nanotube FETs with Pd contacts in on-state current density and Ion/Ioff ratio, but have the advantage of producing all-semiconducting devices.
Reversible electromechanical characteristics of carbon nanotubes underlocal-probe manipulation
Experimental and theoretical elucidation of the electromechanical characteristics of individual single-walled carbonnanotubes (SWNTs) under local-probe manipulation are reported and it is revealed that the conductance of an SWNT sample can be reduced by two orders of magnitude when deformed by an AFM tip.
Hysteresis caused by water molecules in carbon nanotube field-effect transistors
Carbon nanotube field-effect transistors commonly comprise nanotubes lying on SiO2 surfaces exposed to the ambient environment. It is shown here that the transistors exhibit hysteresis in their…
Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy
- Zhuang Liu, C. Davis, W. Cai, Lina He, Xiaoyuan Chen, H. Dai
- Chemistry, BiologyProceedings of the National Academy of Sciences
- 5 February 2008
Functionalization of SWNTs by branched polyethylene-glycol (PEG) chains was developed, enabling thus far the longest SWNT blood circulation up to 1 day, relatively low uptake in the reticuloendothelial system (RES), and near-complete clearance from the main organs in ≈2 months.
Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery
This comprehensive review of carbon nanotube-based drug delivery has shown promise in various In vitro and in vivo experiments including delivery of small interfering RNA, paclitaxel and doxorubicin and electrical nanosensors based on nanotubes provide a label-free approach to biological detection.
Narrow graphene nanoribbons from carbon nanotubes
This work shows an approach to making GNRs by unzipping multiwalled carbon nanotubes by plasma etching of nanot tubes partly embedded in a polymer film that has smooth edges and a narrow width distribution.