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Graphene Oxide Attenuates the Cytotoxicity and Mutagenicity of PCB 52 via Activation of Genuine Autophagy.
  • Y. Liu, Xinan Wang, +10 authors A. Xu
  • Chemistry, Medicine
  • Environmental science & technology
  • 23 February 2016
Graphene oxide (GO), owing to its large surface area and abundance of oxygen-containing functional groups, is emerging as a potential adsorbent for polychlorinated biphenyls (PCBs), which accumulateExpand
Endosulfan isomers and sulfate metabolite induced reproductive toxicity in Caenorhabditis elegans involves genotoxic response genes.
  • H. Du, M. Wang, +6 authors A. Xu
  • Biology, Medicine
  • Environmental science & technology
  • 4 February 2015
Endosulfan is enlisted as one of the persistent organic pollutants (POPs) and exists in the form of its α and β isomers in the environment as well as in the form of endosulfan sulfate, a toxicExpand
Transgenerational effects of diesel particulate matter on Caenorhabditis elegans through maternal and multigenerational exposure.
Diesel particulate matter (DPM) is a dominant contaminant in fine particulate matters (PM2.5) and has been proved to induce serious harmful effects to human beings, including lung cancer, allergic,Expand
Reproductive Toxicity of Endosulfan: Implication From Germ Cell Apoptosis Modulated by Mitochondrial Dysfunction and Genotoxic Response Genes in Caenorhabditis elegans.
  • H. Du, M. Wang, +6 authors A. Xu
  • Biology, Medicine
  • Toxicological sciences : an official journal of…
  • 1 May 2015
Endosulfan as a new member of persistent organic pollutants has been shown to induce reproductive dysfunction in various animal models. However, the action mechanism of endosulfan-producedExpand
Graphene oxide antagonizes the toxic response to arsenic via activation of protective autophagy and suppression of the arsenic-binding protein LEC-1 in Caenorhabditis elegans
Arsenic (As) pollution is a serious global problem and various technologies have been developed for As detoxification. Graphene oxide (GO) with its extraordinary structure and physicochemicalExpand
TiO2 nanoparticles enhance bioaccumulation and toxicity of heavy metals in Caenorhabditis elegans via modification of local concentrations during the sedimentation process.
Unintentionally released titanium dioxide nanoparticles (TiO2 NPs) may co-occur with pre-existing heavy metal pollutants in aquatic environments. However, the interactions between NPs and heavyExpand
Mitochondria and MAPK cascades modulate endosulfan-induced germline apoptosis in Caenorhabditis elegans.
Endosulfan as a new member of persistent organic pollutants has been shown to induce apoptosis in various animal models. However, the mechanism underlying endosulfan-induced apoptosis has not beenExpand
Graphene oxide regulates cox2 in human embryonic kidney 293T cells via epigenetic mechanisms: dynamic chromosomal interactions
Abstract To extend the applications of engineered nanomaterials, such as graphene oxide (GO), it is necessary to minimize cytotoxicity. However, the mechanisms underlying this cytotoxicity areExpand
Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy
Despite treatment of lung cancer with radiotherapy and chemotherapy, the survival rate of lung cancer patients remains poor. Previous studies demonstrated the importance of upregulation ofExpand
Parental exposure to TiO2 NPs promotes the multigenerational reproductive toxicity of Cd in Caenorhabditis elegans via bioaccumulation of Cd in germ cells
Titanium dioxide nanoparticles (TiO2 NPs) can modify the behavior and bioavailability of heavy metals in aquatic environments. However, the influence of TiO2 NPs on the multigenerational impairmentsExpand