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- Publications
- Influence
Anti factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome.
- M. Józsi, S. Strobel, +5 authors P. Zipfel
- Medicine
- Blood
- 1 September 2007
The atypical form of the kidney disease hemolytic uremic syndrome (aHUS) is associated with defective complement regulation. In addition to mutations in complement regulators, factor H (FH)-specific… Expand
Botryorhodines A-D, antifungal and cytotoxic depsidones from Botryosphaeria rhodina, an endophyte of the medicinal plant Bidens pilosa.
- Randa Abdou, K. Scherlach, H. Dahse, I. Sattler, C. Hertweck
- Biology, Medicine
- Phytochemistry
- 2010
An endophytic fungus (Botryosphaeria rhodina) was isolated from the stems of the medicinal plant Bidens pilosa (Asteraceae) that is known for its anti-inflammatory, antiseptic and antifungal effects.… Expand
Growth of keratinocytes on porous films of poly(3-hydroxybutyrate) and poly(4-hydroxybutyrate) blended with hyaluronic acid and chitosan.
- G. Peschel, H. Dahse, +4 authors M. Roth
- Materials Science, Medicine
- Journal of biomedical materials research. Part A
- 15 June 2008
The objective of this study was to develop novel absorbable films suitable for use as a tissue-engineering scaffold for keratinocytes as a therapy for replacement of damaged skin.… Expand
Antimicrobial and anti-inflammatory activity of four known and one new triterpenoid from Combretum imberbe (Combretaceae).
- J. E. Angeh, X. Huang, +4 authors J. Eloff
- Biology, Medicine
- Journal of ethnopharmacology
- 1 March 2007
Combretum imberbe is used widely in Africa inter alia for treating bacterial infections. In addition to four known triterpenoids, 1alpha,3beta-dihydroxy-12-oleanen-29-oic (1),… Expand
Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway
- Andreas Thywissen, T. Heinekamp, +4 authors A. Brakhage
- Biology, Medicine
- Front. Microbio.
- 29 March 2011
Aspergillus fumigatus is the most important air-borne fungal pathogen of humans. The interaction of the pathogen with the host's immune system represents a key process to understand pathogenicity.… Expand
Cleavage of four carbon-carbon bonds during biosynthesis of the griseorhodin a spiroketal pharmacophore.
- Zeynep S Yunt, K. Reinhardt, +6 authors J. Piel
- Chemistry, Medicine
- Journal of the American Chemical Society
- 28 January 2009
The rubromycins, such as gamma-rubromycin, heliquinomycin, and griseorhodin A, are a family of extensively modified aromatic polyketides that inhibit HIV reverse transcriptase and human telomerase.… Expand
New abietane diterpenoids from the mangrove Avicennia marina.
- L. Han, Xueshi Huang, +4 authors I. Sattler
- Biology, Medicine
- Planta medica
- 1 March 2008
Phytochemical investigations of the twigs of Avicennia marina yielded three new abietane diterpenoids 11-hydroxy-8,11,13-abietatriene 12- O-beta-xylopyranoside ( 1), and a pair of inseparable epimers… Expand
Synthesis and characterization of novel 1,2,4-triazine derivatives with antiproliferative activity.
- Fabian Krauth, H. Dahse, H. Rüttinger, P. Frohberg
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 1 March 2010
A series of novel small molecules with a 1,2,4-triazine scaffold was obtained according to a recently published and highly efficient synthetic route. Screening for antiproliferative and cytotoxic… Expand
In vitro cytotoxicity of melleolide antibiotics: structural and mechanistic aspects.
- M. Bohnert, S. Miethbauer, H. Dahse, Johannes Ziemen, M. Nett, D. Hoffmeister
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 1 April 2011
Melleolide sesquiterpene aryl esters are secondary products of the mushroom genus Armillaria. We compared the cytotoxicity of eleven melleolides--five thereof are new natural products--against four… Expand
Terpenes from the Soft Corals Litophyton arboreum and Sarcophyton ehrenbergi
- K. Shaker, M. Müller, M. A. Ghani, H. Dahse, K. Seifert
- Chemistry, Medicine
- Chemistry & biodiversity
- 1 August 2010
The new cembrane diterpene (3E,11E)‐cembra‐3,8(19),11,15‐tetraene‐7α‐ol (1), nephthenol (2), and all‐trans‐peridinin (3) have been isolated from the soft coral Litophyton arboreum. The tetraterpene… Expand