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Valvular heart disease associated with fenfluramine-phentermine.
TLDR
Concerns are raised that fenfluramine-phentermine therapy may be associated with valvular heart disease, which is arouse concern about serious potential adverse effects, including pulmonary hypertension and valvULAR heart disease.
Best practices in managing transition to adulthood for adolescents with congenital heart disease: the transition process and medical and psychosocial issues: a scientific statement from the American
TLDR
Adolescents with congenital heart disease constitute a growing population of individuals for whom a well-planned and well-executed “transition process” is essential to optimize the quality of life, life expectancy, and future productivity of young patients.
Severe aortic stenosis with low transvalvular gradient and severe left ventricular dysfunction:result of aortic valve replacement in 52 patients.
TLDR
Despite severe left ventricular dysfunction, low transvalvular mean gradient, and increased operative mortality, aortic valve replacement was associated with improved functional status, and medium-term survival was related to improved postoperative functional class.
Factors associated with progression of carcinoid heart disease.
TLDR
Serotonin is related to the progression of carcinoid heart disease, and the risk of progressive heart disease is higher in patients who receive chemotherapy than in those who do not, according to a retrospective study conducted to identify such factors.
Noninfectious Ascending Aortitis: A Case Series of 64 Patients
TLDR
Noninfectious ascending aortitis frequently occurs even in the absence of history, symptoms, or signs of giant cell arteritis (GCA) or PMR, and patients should be followed closely, as a majority have additional vascular abnormalities.
Impaired Left Ventricular Mechanics in Pulmonary Arterial Hypertension: Identification of a Cohort at High Risk
TLDR
The pressure loading in PAH results in geometric alterations and functional decline of the RV, with marked reduction in RV systolic strain.
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