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Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes
TLDR
It is indicated that hypoxia enhances HDAC function and that HDAC is closely involved in angiogenesis through suppression of Hypoxia-responsive tumor suppressor genes.
Acetyl- and butyrylcholinesterase inhibitory activities of sterols and phlorotannins from Ecklonia stolonifera
TLDR
It has been suggested that the inhibition of these enzymes by the sterols and phlorotannins derived from marine brown algae could be a useful approach for the treatment of Alzheimer’s disease.
Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: A possible signal for vessel development
TLDR
The data clearly show that hypoxia marker immunoreactivity was highly detected in developing neural tubes, heart, and intersomitic mesenchyme at an early stage of organogenesis, suggesting that Hypoxia may exist in the early stages of embryo development.
The molecular inflammatory process in aging.
TLDR
In this review, inflammation is examined as a possible underlying basis for the molecular alterations that link aging and age-related pathological processes and the involvement of another super family of transcription factors, PPARs as regulators of proinflammatory responses and NF-kappaB signaling pathway is described.
Curcumin Stimulates Proliferation of Embryonic Neural Progenitor Cells and Neurogenesis in the Adult Hippocampus*
TLDR
It is suggested that curcumin can stimulate developmental and adult hippocampal neurogenesis, and a biological activity that may enhance neural plasticity and repair is suggested.
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