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Dietary fat increases solid tumor growth and metastasis of 4T1 murine mammary carcinoma cells and mortality in obesity-resistant BALB/c mice
TLDR
Dietary fat increases mammary tumor growth and metastasis, thereby increasing mortality in obesity-resistant mice, and protein levels of the urokinase-type plasminogen activator, ICAM-1, and vascular cell adhesion molecule-1 were increased, but plasmine activator inhibitor-1 levels were decreased in the lungs of the HFD group.
Modern analytical methods for the detection of food fraud and adulteration by food category.
This review provides current information on the analytical methods used to identify food adulteration in the six most adulterated food categories: animal origin and seafood, oils and fats, beverages,
Structure-activity relationship of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds.
TLDR
Results indicate that the presence of the alanyl group and the absence of the oxo group are essential for the manifestation of neuroprotective activity against ischemic insults and scavenging of OH radical, with SAC surfacing as a potent neuroprotectant.
S-Allyl-l-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase
TLDR
The present results indicate that SAC exert its neuroprotective effect by scavenging ONOO− and inhibiting the ERK signaling pathway activated during initial hypoxic/ischemic insults.
NF-kappaB activates transcription of the RNA-binding factor HuR, via PI3K-AKT signaling, to promote gastric tumorigenesis.
TLDR
HuR is a direct transcription target of NF-kappaB; its activation in gastric cancer cell lines depends on phosphatidylinositol 3-kinase/AKT signaling and HuR activation by this pathway has proliferative and antiapoptotic effects on Gastric cancer cells.
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