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Phosphorylation of Phosphatidate Phosphatase Regulates Its Membrane Association and Physiological Functions in Saccharomyces cerevisiae
The Saccharomyces cerevisiae PAH1-encoded phosphatidate phosphatase (PAP) catalyzes the penultimate step in the synthesis of triacylglycerol and plays a role in the transcriptional regulation ofExpand
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Pho85p-Pho80p Phosphorylation of Yeast Pah1p Phosphatidate Phosphatase Regulates Its Activity, Location, Abundance, and Function in Lipid Metabolism*♦
Background: Yeast Pah1p phosphatidate phosphatase dephosphorylates phosphatidate to generate diacylglycerol for lipid synthesis. Results: Pah1p was phosphorylated by the Pho85p-Pho80p proteinExpand
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Angiotensin I-converting enzyme inhibitor from Grifola frondosa
To investigate the hypotensive compounds from edible mushroom, extracts from 10 fruit bodies of mushrooms were screened for the inhibitory activity against angiotensin I converting enzyme (ACE). TheExpand
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Ellagic Acid Suppresses Lipid Accumulation by Suppressing Early Adipogenic Events and Cell Cycle Arrest
Ellagic acid (EA) is a natural polyphenol found in various fruits and vegetables. In this study, we examined the inhibitory effect of EA on fat accumulation in 3T3‐L1 cells during adipogenesis. OurExpand
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Dieckol, a major phlorotannin in Ecklonia cava, suppresses lipid accumulation in the adipocytes of high-fat diet-fed zebrafish and mice: Inhibition of early adipogenesis via cell-cycle arrest and
SCOPE Dieckol is a major polyphenol of Ecklonia cava. This study demonstrates a mechanistic role for dieckol in the suppression of lipid accumulation using three models. METHODS AND RESULTS MiceExpand
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Phosphorylation of Yeast Phosphatidylserine Synthase by Protein Kinase A
The CHO1-encoded phosphatidylserine synthase from Saccharomyces cerevisiae is phosphorylated and inhibited by protein kinase A in vitro. CHO1 alleles bearing Ser46 → Ala and/or Ser47 → Ala mutationsExpand
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Blockade of lipid accumulation by silibinin in adipocytes and zebrafish.
Silibinin is a compound present mainly in milk thistle. In this study, we investigated the mechanism by which silibinin suppresses adipogenesis of 3T3-L1 cells, and evaluated the anti-adipogenicExpand
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Pycnogenol® Inhibits Lipid Accumulation in 3T3‐L1 Adipocytes with the Modulation of Reactive Oxygen Species (ROS) Production Associated with Antioxidant Enzyme Responses
Pycnogenol® is a group of flavonoids with antioxidant effects. Adipogenesis is the process of adipocyte differentiation. It causes the increase of lipids as well as ROS (reactive oxygen species).Expand
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Characterization of the odor-active volatiles in citrus Hyuganatsu (Citrus tamurana Hort. ex Tanaka).
The volatile components of Hyuganatsu (Citrus tamurana Hort. ex Tanaka) peel oil, isolated by cold-pressing, were investigated by chemical and sensory analyses. According to chemical analysis by GCExpand
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Kaempferol suppresses lipid accumulation by inhibiting early adipogenesis in 3T3-L1 cells and zebrafish.
Kaempferol is a flavonoid present in Kaempferia galanga and Opuntia ficus indica var. saboten. Recent studies have suggested that it has anti-oxidant, anti-inflammatory, anti-cancer, and anti-obesityExpand
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