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- Publications
- Influence
A High-Resolution Absolute-Dated Late Pleistocene Monsoon Record from Hulu Cave, China
- Y. Wang, H. Cheng, +4 authors J. A. Dorale
- Geology, Medicine
- Science
- 14 December 2001
Oxygen isotope records of five stalagmites from Hulu Cave near Nanjing bear a remarkable resemblance to oxygen isotope records from Greenland ice cores, suggesting that East Asian Monsoon intensity… Expand
Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle.
- H. Cheng, W. Lederer, M. Cannell
- Chemistry, Medicine
- Science
- 29 October 1993
Spontaneous local increases in the concentration of intracellular calcium, called "calcium sparks," were detected in quiescent rat heart cells with a laser scanning confocal microscope and the… Expand
Relaxation of Arterial Smooth Muscle by Calcium Sparks
- M. Nelson, H. Cheng, +4 authors W. Lederer
- Chemistry, Medicine
- Science
- 27 October 1995
Local increases in intracellular calcium ion concentration ([Ca2+]i) resulting from activation of the ryanodine-sensitive calcium-release channel in the sarcoplasmic reticulum (SR) of smooth muscle… Expand
Integration of Plant Responses to Environmentally Activated Phytohormonal Signals
- P. Achard, H. Cheng, +6 authors N. Harberd
- Biology, Medicine
- Science
- 6 January 2006
Plants live in fixed locations and survive adversity by integrating growth responses to diverse environmental signals. Here, we show that the nuclear-localized growth-repressing DELLA proteins of… Expand
The control of calcium release in heart muscle.
- M. Cannell, H. Cheng, W. Lederer
- Chemistry, Medicine
- Science
- 19 May 1995
The control of calcium release from intracellular stores (the sarcoplasmic reticulum) in cardiac muscle was examined with the use of a confocal microscope and voltage clamp techniques. Depolarization… Expand
Calcium sparks and [Ca2+]i waves in cardiac myocytes.
- H. Cheng, M. Lederer, W. Lederer, M. Cannell
- Chemistry, Medicine
- The American journal of physiology
- 1996
Local elevations in intracellular calcium ("Ca2+ sparks") in heart muscle are elementary sarcoplasmic reticulum (SR) Ca(2+)-release events. Ca2+ sparks occur at a low rate in quiescent cells but can… Expand
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure.
- A. M. Gómez, H. Valdivia, +6 authors W. Lederer
- Chemistry, Medicine
- Science
- 2 May 1997
Cardiac hypertrophy and heart failure caused by high blood pressure were studied in single myocytes taken from hypertensive rats (Dahl SS/Jr) and SH-HF rats in heart failure. Confocal microscopy and… Expand
Direct measurement of SR release flux by tracking ‘Ca2+ spikes’ in rat cardiac myocytes
- L. Song, J. Sham, M. Stern, E. Lakatta, H. Cheng
- Chemistry, Medicine
- The Journal of physiology
- 1 November 1998
1 Ca2+ release flux across the sarcoplasmic reticulum (SR) during cardiac excitation‐contraction coupling was investigated using a novel fluorescence method. Under whole‐cell voltage‐clamp… Expand
Direct Determination of the Timing of Sea Level Change During Termination II
- C. Gallup, H. Cheng, F. W. Taylor, R. Edwards
- Geology, Medicine
- Science
- 11 January 2002
An outcrop within the last interglacial terrace on Barbados contains corals that grew during the penultimate deglaciation, or Termination II. We used combined 230Th and231Pa dating to determine that… Expand
Relation between the sarcolemmal Ca2+ current and Ca2+ sparks and local control theories for cardiac excitation-contraction coupling.
- L. Santana, H. Cheng, A. M. Gómez, M. Cannell, W. Lederer
- Chemistry, Medicine
- Circulation research
- 1996
Ca2+ sparks, the elementary events underlying excitation-contraction (E-C) coupling, occur when sarcoplasmic reticulum (SR) Ca2+ release channels open. They are activated locally by Ca2+ influx… Expand