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Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
Genome-wide association (GWA) studies have identified multiple loci at which common variants modestly but reproducibly influence risk of type 2 diabetes (T2D). Established associations to common and… Expand
Distribution and clinical correlates of viral and host genotypes in Chinese patients with chronic hepatitis C virus infection
- H. Rao, Lai Wei, +32 authors H. Zhuang
- Journal of gastroenterology and hepatology
- 19 February 2014
Chronic hepatitis C virus (HCV) infection is relatively frequent in China. This study investigated the clinical, demographic, and viral and host genetic characteristics that may influence disease… Expand
Epidemiological characteristics and clinical features of 32 critical and 67 noncritical cases of COVID-19 in Chengdu
Abstract Background In December 2019, Wuhan, China, experienced an outbreak of coronavirus (COVID-19). The number of cases has… Expand
Expression of P450 and nuclear receptors in normal and end-stage Chinese livers.
AIM To investigate the expression of P450 enzyme genes by using end-stage liver disease samples and trimmed normal Chinese donor livers. METHODS The end-stage liver disease samples [n = 93,… Expand
Acute myocardial injury is common in patients with COVID-19 and impairs their prognosis
Objective We sought to explore the prevalence and immediate clinical implications of acute myocardial injury in a cohort of patients with COVID-19 in a region of China where medical resources are… Expand
mRNA expression of BRCA1, PIAS1, and PIAS4 and survival after second-line docetaxel in advanced gastric cancer.
- J. Wei, C. Costa, +12 authors B. Liu
- Biology, Medicine
- Journal of the National Cancer Institute
- 19 October 2011
Breast cancer susceptibility gene 1 (BRCA1) has a central role in chemotherapy-induced DNA damage response. The protein inhibitor of activated STAT (PIAS) family of proteins, PIAS1 and PIAS4, are… Expand
Alterations of plasma inflammatory biomarkers in the healthy and chronic obstructive pulmonary disease patients with or without acute exacerbation.
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of mortally and morbidity, associated with acute exacerbations (AECOPD) resulted from smoking, infection or air pollution.… Expand
Tumor Necrosis Factor Receptor Levels Are Associated With Carotid Atherosclerosis
Background and Purpose— Recent evidence suggests that atherosclerosis is an inflammatory condition. Serum levels of inflammatory markers may serve as measures of the severity of atherosclerosis and… Expand
Intracranial clear cell meningioma: a clinicopathologic study of 15 cases
ObjectClear cell meningioma (CCM) is a rare histological variant of meningioma. CCM has a high recurrence rate and aggressiveness. In this study, we reviewed our experience in the treatment of the… Expand
Cloning, Expression, and Developmental and Dietary Regulations of a Chicken Intestinal Peptide Transporter and Characterization and Regulation of an Ovine Gastrointestinal Peptide Transporter…
- H. Chen
- 28 September 2001
...............................................................................................ii Acknowledgments… Expand