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Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2
Alternative hosts and model animals The severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) pandemic may have originated in bats, but how it made its way into humans is unknown. Because of… Expand
Properties and Dissemination of H5N1 Viruses Isolated during an Influenza Outbreak in Migratory Waterfowl in Western China
ABSTRACT H5N1 influenza A viruses are widely distributed among poultry in Asia, but until recently, only a limited number of wild birds were affected. During late April through June 2005, an outbreak… Expand
Emergence and predominance of an H5N1 influenza variant in China
- G. Smith, X. H. Fan, +11 authors Y. Guan
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 7 November 2006
The development of highly pathogenic avian H5N1 influenza viruses in poultry in Eurasia accompanied with the increase in human infection in 2006 suggests that the virus has not been effectively… Expand
Evolution of H9N2 influenza viruses from domestic poultry in Mainland China.
H9N2 viruses have circulated in domestic poultry in Mainland China since 1994, and an inactivated vaccine has been used in chickens to control the disease since 1998. The present study analyzed 27… Expand
Are Ducks Contributing to the Endemicity of Highly Pathogenic H5N1 Influenza Virus in Asia?
- K. M. Sturm-Ramirez, D. J. Hulse-Post, +13 authors R. Webster
- Biology, Medicine
- Journal of Virology
- 1 September 2005
ABSTRACT Wild waterfowl are the natural reservoir of all influenza A viruses, and these viruses are usually nonpathogenic in these birds. However, since late 2002, H5N1 outbreaks in Asia have… Expand
Protective efficacy in chickens, geese and ducks of an H5N1-inactivated vaccine developed by reverse genetics.
We generated a high-growth H5N1/PR8 virus by plasmid-based reverse genetics. The virulence associated multiple basic amino acids of the HA gene were removed, and the resulting virus is attenuated for… Expand
Molecular Basis of Replication of Duck H5N1 Influenza Viruses in a Mammalian Mouse Model
ABSTRACT We recently analyzed a series of H5N1 viruses isolated from healthy ducks in southern China since 1999 and found that these viruses had progressively acquired the ability to replicate and… Expand
The NS1 Gene Contributes to the Virulence of H5N1 Avian Influenza Viruses
ABSTRACT In the present study, we explored the genetic basis underlying the virulence and host range of two H5N1 influenza viruses in chickens. A/goose/Guangdong/1/96 (GS/GD/1/96) is a highly… Expand
H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet
H7N9 Adaptation Puzzling and alarming reports of an outbreak in early 2013 of human infections by a low-pathogenicity avian influenza virus has rocked the poultry industry in central eastern China… Expand
Evolution and adaptation of H5N1 influenza virus in avian and human hosts in Indonesia and Vietnam.
Highly pathogenic avian influenza virus H5N1 is endemic in poultry in East and Southeast Asia with disease outbreaks recently spreading to parts of central Asia, Europe and Africa. Continued… Expand