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Low-dose CT via convolutional neural network.
TLDR
We propose a new noise reduction method for low-dose CT via deep learning without accessing original projection data. Expand
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A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes.
Heat-stable nucleoid structuring protein (H-NS) is an abundant prokaryotic protein that plays important roles in organizing chromosomal DNA and gene silencing. Two controversial binding modes wereExpand
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Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation
The force-dependent interaction between talin and vinculin plays a crucial role in the initiation and growth of focal adhesions. Here we use magnetic tweezers to characterise the mechano-sensitiveExpand
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MPIPP: an automatic profile-guided parallel process placement toolset for SMP clusters and multiclusters
TLDR
SMP clusters and multiclusters are widely used to execute message-passing parallel applications. Expand
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A novel method for protein secondary structure prediction using dual‐layer SVM and profiles
TLDR
A high‐performance method was developed for protein secondary structure prediction based on the dual‐layer support vector machine (SVM) and position‐specific scoring matrices (PSSMs). Expand
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AnimalTFDB: a comprehensive animal transcription factor database
TLDR
In this study, based on manual literature reviews, we collected and curated 72 TF families for animals, which is currently the most complete list of TF families in animals. Expand
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MeMo: a web tool for prediction of protein methylation modifications
TLDR
Protein methylation is an important and reversible post-translational modification of proteins (PTMs), which governs cellular dynamics and plasticity. Expand
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Improved high-force magnetic tweezers for stretching and refolding of proteins and short DNA.
Although magnetic tweezers have many unique advantages in terms of specificity, throughput, and force stability, this tool has had limited application on short tethers because accurate measurement ofExpand
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Genetic relationship and diversity of Mangifera indica L.: revealed through SCoT analysis
Mango (Mangifera indica L.) is one of the most economically grown fruits in the tropical and subtropical areas around the world. In the present study, start codon targeted (SCoT) markers wereExpand
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Inferring protein function by domain context similarities in protein-protein interaction networks
TLDR
This paper presents a novel protein function prediction method that combines protein domain composition information and PPI networks to predict protein functions. Expand
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