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Analysis of binding interaction between puerarin and bovine serum albumin by multi-spectroscopic method.
It was found that both static quenching and non-radiation energy transfer were the main reasons for the fluorescence quenched, and the interaction of puerarin and BSA was driven mainly by hydrophobic forces. Expand
Structure-affinity relationship of flavones on binding to serum albumins: effect of hydroxyl groups on ring A.
Four flavones (flavone, 7-hydroxyflavone, chrysin, and baicalein) sharing the same B- and C-ring structure but a different numbers of hydroxyl groups on the A-ring were studied for their affinitiesExpand
Green tea polyphenol (–)-epigallocatechin-3-gallate enhances the inhibitory effect of huperzine A on acetylcholinesterase by increasing the affinity with serum albumin
Results indicate that addition of EGCG to huperZine A can reduce the dose of huperzine A required compared with huper Zine A alone, and the enhancement and complementary effect of E GCG on huper zine A activity may partly be due to the antioxidant property of EgcG. Expand
Intracellular signaling pathways of inflammation modulated by dietary flavonoids: The most recent evidence
  • L. Chen, Hui Teng, +5 authors J. Xiao
  • Biology, Medicine
  • Critical reviews in food science and nutrition
  • 22 November 2018
The present review attempted to summarize and highlight a broad range of inflammation-associated signaling pathways modulated by flavonoids, and identified the main structural features required for the modulation of these inflammation-related pathways (hydroxylation pattern, C2=C3 double bond). Expand
Glycosylation of dietary flavonoids decreases the affinities for plasma protein.
This work mainly concerns the effect of glycosylation of flavonoids on the affinities for BSA, and partly supports that flavonoid aglycones are more easily absorbed than Flavonoid glycosides. Expand
Molecular property-affinity relationship of flavanoids and flavonoids for HSA in vitro.
The affinities for HSA increased with increasing partition coefficients and decreased with increasing hydrogen bond donor and acceptor numbers of flava(o)noids, which suggested that the binding interaction was mainly caused by hydrophobic forces. Expand
Bioactive compounds from marine macroalgae and their hypoglycemic benefits
Diabetes mellitus is a group of chronic metabolic disorders characterized by hyperglycemia due to defects in insulin action and/or secretion. It is a worldwide problem which has led to illness andExpand
Microbial biotransformation of bioactive flavonoids.
The bioactive flavonoids are considered as the most important phytochemicals in food, which exert a wide range of biological benefits for human being and the existing knowledge on the production and biotransformation of flavonoid by various microbes is summarized. Expand
Study of the interaction between baicalin and bovine serum albumin by multi-spectroscopic method
Abstract The interaction of baicalin and bovine serum albumin (BSA) was investigated using fluorescence spectroscopy (FS), resonance light scattering spectroscopy (RLS), and ultraviolet spectroscopyExpand
Screening of anti-platelet aggregation agents from Panax notoginseng using human platelet extraction and HPLC-DAD-ESI-MS/MS.
The results showed that the nucleosides adenosine and guanosine mainly contributed to the anti-platelet aggregation of Sanqi, suggesting that human platelet extraction combined with HPLC-DAD-ESI-MS/MS is a useful method for screening anti- platelet aggregation agents from Chinese medicines. Expand