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UV Irradiation Triggers Ubiquitin-Dependent Degradation of p21WAF1 to Promote DNA Repair
View on Elsevier
Survival and Implantation of Escherichia coli in the Intestinal Tract
TLDR
Limiting of growth must be regarded as the primary mechanism controlling bacterial populations in the large intestine because two or more bacterial strains that compete in the gut for the same limiting nutrient can coexist, if the metabolically less efficient strains have specific adhesion sites available.
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Mechanisms That Control Bacterial Populations in Continuous-Flow Culture Models of Mouse Large Intestinal Flora
TLDR
The results obtained are compatible with the hypothesis that the populations of most indigenous intestinal bacteria are controlled by one or a few nutritional substrates which a given strain can utilize most efficiently in the presence of H(2)S and at the prevailing conditions of pH and anaerobiosis.
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Regulation of p21(WAF1/CIP1) stability by WISp39, a Hsp90 binding TPR protein.
View on PubMed
Experimental and Mathematical Models of Escherichia coli Plasmid Transfer In Vitro and In Vivo
Little is known about the factors that govern plasmid transfers in natural ecosystems such as the gut. The consistent finding by earlier workers that plasmid transfer in the normal gut can be…
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The large subunit of replication factor C promotes cell survival after DNA damage in an LxCxE motif- and Rb-dependent manner.
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A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells.
TLDR
It is concluded that amino acid residues 481–728 of human RF‐Cp145 are critical and act as a dominant negative mutant ofRF‐C function in DNA replication in vivo.
View on Wiley
Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells
TLDR
Thymocytes from p21 transgenic mice are hypersensitive to radiation induced programmed cell death and it is suggested that the radiation hypersensitivity of p 21 transgenic thymocytes involves p53 dependent pathway and signals in addition to p21.
View on Springer
p70 lupus autoantigen binds the enhancer of the T-cell receptor beta-chain gene.
TLDR
Data suggest that the p70 lupus autoantigen binds a critical motif in the beta enhancer and probably regulates TCR beta gene expression.
View on PubMed
Cell Cycle-dependent Phosphorylation of the Large Subunit of Replication Factor C (RF-C) Leads to Its Dissociation from the RF-C Complex*
TLDR
It is demonstrated that phosphorylated RFCp145 is indeed dissociated from RF-Cp40 and RF-cp37 in vivo and suggested that destabilization of theRF-C complex by CDKs may inactivate the RF- C complex at the end of S phase.
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