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Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials
TLDR
The findings suggest that 20 mg per day rimonabant increases the risk of psychiatric adverse events--ie, depressed mood disorders and anxiety-despite depressed mood being an exclusion criterion in these trials. Expand
EULAR evidence-based recommendations for the management of fibromyalgia syndrome
TLDR
Nine recommendations for the management of fibromyalgia syndrome were developed using a systematic review and expert consensus using a Delphi process. Expand
Effect of weight reduction in obese patients diagnosed with knee osteoarthritis: a systematic review and meta-analysis
TLDR
Meta-regression analysis indicated that physical disability of patients with knee OA and overweight diminished after a moderate weight reduction regime, and supported that a weight loss of >5% should be achieved within a 20-week period—that is, 0.25% per week. Expand
Test-retest reliability of trunk accelerometric gait analysis.
TLDR
The method was found to be reliable and may have a definite potential in clinical gait analysis and absolute reliability was determined using measurement error (ME). Expand
A randomized controlled trial of aquatic and land-based exercise in patients with knee osteoarthritis.
TLDR
Only land-based exercise showed some improvement in pain and muscle strength compared with the control group, while no clinical benefits were detectable after aquatic exercise compared withThe control group; however, aquatic exercise has significantly less adverse effects compared with a land- based programme. Expand
Isokinetic and isometric muscle strength in a healthy population with special reference to age and gender
TLDR
The aim of the present study was to measure a set of normal values for isometric and isokinetic muscle strength for all the major joint movements of the body and create a basis for comparison of the muscle strength of an individual with the expected value in a normal population. Expand
A randomized, placebo-controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis.
TLDR
A statistically significant effect of ginger extract could only be demonstrated by explorative statistical methods in the first period of treatment before cross-over, while a significant difference was not observed in the study as a whole. Expand
Effect of whole body vibration exercise on muscle strength and proprioception in females with knee osteoarthritis.
TLDR
The WBV-exercise is a time-saving and safe method for rehabilitation of women with knee-OA and showed improved TDPM, which was found to be a significant increase in muscle strength and proprioception. Expand
Chronic widespread pain in the spectrum of rheumatological diseases.
TLDR
It is important for health professionals to be aware of this syndrome and to diagnose the patients to avoid a steady increase in diagnostic tests, and evidence points to central sensitization as an important neurophysiological aberration in the development of FMS. Expand
Gait changes in patients with knee osteoarthritis are replicated by experimental knee pain
TLDR
Changes in knee moments during walking following experimental knee pain in healthy volunteers are investigated, and whether these changes replicated the joint moments observed in medial knee OA patients. Expand
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