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Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics
Available data on the absorption, metabolism and pharmacokinetics of coenzyme Q10 (CoQ10) are reviewed in this paper. CoQ10 has a fundamental role in cellular bioenergetics. CoQ10 is also an… Expand
Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations.
Plasma coenzyme Q10 (CoQ10) response to oral ingestion of various CoQ10 formulations was examined. Both total plasma CoQ10 and net increase over baseline CoQ10 concentrations show a gradual increase… Expand
Comparison of plasma alpha and gamma tocopherol levels following chronic oral administration of either all-rac-alpha-tocopheryl acetate or RRR-alpha-tocopheryl acetate in normal adult male subjects.
- H. Baker, G. Handelman, +4 authors O. Frank
- Chemistry, Medicine
- The American journal of clinical nutrition
- 1 March 1986
Vitamin E was administered orally (400 IU twice a day) to adult male humans for 28 days as either dl-alpha-tocopheryl acetate (all-rac-alpha-tocopheryl acetate) or d-alpha-tocopheryl acetate… Expand
Dietary coenzyme Q10 and vitamin E alter the status of these compounds in rat tissues and mitochondria.
- W. Ibrahim, H. Bhagavan, R. K. Chopra, C. Chow
- Biology, Medicine
- The Journal of nutrition
- 1 September 2000
Vitamin E (VE) and coenzyme Q (CQ) are essential for maintaining functions and integrity of mitochondria, and high concentrations of these compounds are found in their inner membranes. This study was… Expand
A simple gravimetric technique for measurement of cerebral edema.
A simple method was developed for the laboratory preparation of gradient columns of specific gravity used in measurement of brain-tissue water. By this automated technique, virtually linear and… Expand
Relative bioavailability of coenzyme Q10 formulations in human subjects.
- R. K. Chopra, R. Goldman, S. Sinatra, H. Bhagavan
- International journal for vitamin and nutrition…
The relative bioavailability of typical commercially available forms of coenzyme Q10 (CoQ10) was compared with that of Q-Gel, a new solubilized form of CoQ10, in human subjects in two separate… Expand
A randomized trial of replacement antioxidant vitamin therapy for neutrophil locomotory dysfunction in blunt trauma.
- E. Maderazo, C. Woronick, N. Hickingbotham, L. Jacobs, H. Bhagavan
- The Journal of trauma
- 1 August 1991
Studies in patients with serious trauma indicate that the observed neutrophil (PMN) locomotory dysfunction is partly the result of auto-oxidation as shown by evidence of preactivation, diminished… Expand
A preliminary study of the effect of pyridoxine administration in a subgroup of hyperkinetic children: a double-blind crossover comparison with methylphenidate.
- M. Coleman, G. Steinberg, +5 authors L. deVeau
- Psychology, Medicine
- Biological psychiatry
- 1 October 1979
A small sample of six patients with the putative "hyperkinetic syndrome" participated in a research protocol comparing administration of pyridoxine, methylphenidate, and placeboes. The children had… Expand
Potential role of ubiquinone (coenzyme Q10) in pediatric cardiomyopathy.
Pediatric cardiomyopathy (PCM) represents a group of rare and heterogeneous disorders that often results in death. While there is a large body of literature on adult cardiomyopathy, all of the… Expand
Coenzyme Q 10 and Neoplasia: Overview of Experimental and Clinical Evidence*
36.1 The Integration of Cancer, Immune System, Aging, and Coenzyme Q .............................599 36.1.1 The View from Afar… Expand