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The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11‐59K protein
U11 and U12 interact cooperatively with the 5′ splice site and branch site of pre‐mRNA as a stable preformed di‐snRNP complex, thereby bridging the 5′ and 3′ ends of the intron within the… Expand
Crystal structures of the antitermination factor NusB from Thermotoga maritima and implications for RNA binding.
NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibits… Expand
Investigational drugs for pruritus
Introduction: Chronic pruritus (CP), defined as itch lasting for > 6 weeks, is a burdensome symptom of several different diseases, dermatological and systemic, with a high negative impact on the… Expand
The U 11 / U 12 snRNP 65 K protein acts as a molecular bridge , binding the U 12 snRNA and U 1159 K protein
U11 and U12 interact cooperatively with the 50 splice site and branch site of pre-mRNA as a stable preformed di-snRNP complex, thereby bridging the 50 and 30 ends of the intron within the… Expand
Functional stabilization of an RNA recognition motif by a noncanonical N-terminal expansion.
RNA recognition motifs (RRMs) constitute versatile macromolecular interaction platforms. They are found in many components of spliceosomes, in which they mediate RNA and protein interactions by… Expand
[Neuropeptides and their receptors as a molecular explanation for sensitive skin].
- H. Benecke, S. Schneider, T. Lotts, H. Hatt, T. Luger, S. Ständer
- Der Hautarzt; Zeitschrift fur Dermatologie…
The concept of sensitive skin represents a symptom of physiological reactions rather than a disease entity. According to epidemiological studies, up to 50% of adults report on sensitivity of the face… Expand