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The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11‐59K protein
U11 and U12 interact cooperatively with the 5′ splice site and branch site of pre‐mRNA as a stable preformed di‐snRNP complex, thereby bridging the 5′ and 3′ ends of the intron within theExpand
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Crystal structures of the antitermination factor NusB from Thermotoga maritima and implications for RNA binding.
NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibitsExpand
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Investigational drugs for pruritus
Introduction: Chronic pruritus (CP), defined as itch lasting for > 6 weeks, is a burdensome symptom of several different diseases, dermatological and systemic, with a high negative impact on theExpand
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The U 11 / U 12 snRNP 65 K protein acts as a molecular bridge , binding the U 12 snRNA and U 1159 K protein
U11 and U12 interact cooperatively with the 50 splice site and branch site of pre-mRNA as a stable preformed di-snRNP complex, thereby bridging the 50 and 30 ends of the intron within theExpand
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Functional stabilization of an RNA recognition motif by a noncanonical N-terminal expansion.
RNA recognition motifs (RRMs) constitute versatile macromolecular interaction platforms. They are found in many components of spliceosomes, in which they mediate RNA and protein interactions byExpand
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[Neuropeptides and their receptors as a molecular explanation for sensitive skin].
The concept of sensitive skin represents a symptom of physiological reactions rather than a disease entity. According to epidemiological studies, up to 50% of adults report on sensitivity of the faceExpand
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T. maritima NusB, P3221
T. maritima NusB, P3121, Form 2
T. maritima NusB, P212121
T. maritima NusB, P3121, Form 1