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Synaptic differentiation of a single motor neuron: conjoint definition of transmitter release, presynaptic calcium signals, and ultrastructure
This work investigated quantal release properties, calcium signals, and ultrastructure of presynaptic terminals to elucidate factors that could account for the physiological differences in excitatory postsynaptic potentials of opener muscle in the walking legs of the crayfish.
Fast calcium signals in Drosophila motor neuron terminals.
- G. Macleod, M. Hegström-Wojtowicz, M. Charlton, H. Atwood
- BiologyJournal of neurophysiology
- 1 November 2002
The very rapid decay of the calcium signal following a single AP indicates a previously unreported fast calcium extrusion mechanism in Drosophila motor neuron terminals well suited for sustaining physiological processes during the high rates of impulse activity which drive locomotor activity.
Differential physiology and morphology of motor axons to ventral longitudinal muscles in larval Drosophila
Morphological and physiological characteristics of the two major motor axons supplying the commonly studied ventral longitudinal muscle fibers of third‐instar Drosophila melanogaster larvae were investigated and it was shown that the axon with the smaller varicosities generates a large excitatory junction potential (EJP) in muscle 6 and that the AXS generates a smaller EJP.
Activity-induced changes in synaptic release sites at the crayfish neuromuscular junction
Electrophysiological studies suggest that the number of “active” synapses contributing transmitter quanta at low frequencies of stimulation increases during and after a train of high-frequency stimulation, but not all released quanta produce a voltage change in the postsynaptic muscle cell.
Quantal measurement and analysis methods compared for crayfish and Drosophila neuromuscular junctions, and rat hippocampus
Synaptic physiology and mitochondrial function in crayfish tonic and phasic motor neurons.
Evidence is provided that mitochondrial oxidative metabolism is important for sustaining synaptic transmission during maintained stimulation of tonic and phasic motor neurons and the hypothesis that synaptic fatigue resistance is dependent on mitochondrial function in crayfish motor axons is tested.
Quantal release at visualized terminals of a crayfish motor axon: Intraterminal and regional differences
- R. Cooper, C. C. Harrington, L. Marin, H. Atwood
- BiologyThe Journal of comparative neurology
- 25 November 1996
Synaptic transmission was measured at visualized terminal varicosities of the motor axon providing the sole excitatory innervation of the “opener” muscle in walking legs of crayfish (Procambarus…
Synaptic transmission in decentralized axons of rock lobster
It appears that the basic mechanism that controls the time course of evoked release is altered in degenerating terminals in lobster deep abdominal extensor muscles.
Imaging of calcium in Drosophila larval motor nerve terminals.
At the single-synapse level, the secretory efficacy of Is synapses is greater than that of Ib synapses, but the data show that factors other than differences in Ca2+ entry may govern the strength of synaptic transmission.
Activity‐Dependent Recruitment of Silent Synapses a
The results indicate that responding units, hypothesized to be transmitting synapses, can be recruited to active transmission from an unresponsive pool by tetanic activity, and that protein phosphorylation is required for long-lasting changes to occur.