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Epidermal growth factor receptor (EGFR) overexpression in triple-negative breast cancer: association with clinicopathologic features and prognostic parameters
IntroductionTriple-negative breast cancers are a poor prognostic group of breast cancers that don’t respond to conventional hormonal and her2neu targeted therapy. A subset of triple-negative breastExpand
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Ki67 index in intrinsic breast cancer subtypes and its association with prognostic parameters
ObjectivesKi67 is the most commonly used marker to evaluate proliferative index in breast cancer, however no cutoff values have been clearly defined for high ki67 index. Cancer management should beExpand
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ERG oncoprotein expression in prostatic acinar adenocarcinoma; clinicopathologic significance
ObjectivesT/E fusion results in constitutive expression of ERG oncoprotein resulting in enhanced proliferation and invasive potential of prostatic cancer cells. In the present study we aimed toExpand
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The Importance of Melanocortin Receptors and Their Agonists in Pulmonary Disease
Melanocortin agonists are ancient neuropeptides that have steroidogenesis and anti-inflammatory properties. They activate melanocortin receptors (MCR), a family of five seven-transmembrane G-proteinExpand
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Recognizing Barotrauma as an Unexpected Complication of High Flow Nasal Cannula
W E D N E S D A Y F E L L O W S C A S E R E P O R T P O S T E R S INTRODUCTION: Spontaneous pneumomediastinum (SPM) is a rare clinical condition recognized as the presence of free air in theExpand
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Epidermal growth factor receptor (EGFR) overexpression in endometrial carcinoma: association with histopathologic parameters
BackgroundEpidermal growth factor receptor (EGFR) is a cellular oncoprotein which is overexpressed in many human cancers including a subset of endometrial cancers. Immunohistochemical (IHC)Expand
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Lack of tocilizumab effect on mortality in COVID19 patients
Off-label tocilizumab use in COVID-19 patients reflects concern for cytokine release syndrome. Comparison of matched COVID-19 pneumonia patients found elevated IL-6 levels correlated with mortalityExpand
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Role of IgG against N-protein of SARS-CoV2 in COVID19 clinical outcomes
The Nucleocapsid Protein (N Protein) of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV2) is located in the viral core. Immunoglobulin G (IgG) targeting N protein is detectable in the serumExpand
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Mycobacterium abscessus—Bronchial Epithelial Cells Cross-Talk Through Type I Interferon Signaling
Introduction: Mycobacteria are aerobic non-motile organisms with lipid rich, hydrophobic cell walls that render them resistant to antibiotics. While there are over 150 different species of NTM,Expand
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Prognostic significance of p16 immunohistochemical expression in urothelial carcinoma
Backgroundp16 is the protein product of most commonly involved gene in bladder carcinogenesis. Therefore, we performed an immunohistochemical study to evaluate association of p16 overexpression withExpand
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