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Nephroprotective potential of selenium and taurine against mercuric chloride induced nephropathy in rats
Abstract The study was aimed to estimate whether pre-treatment with sodium selenite or taurine would reverse kidney damage induced by intraperitoneal injection of mercuric chloride in rats. AnimalsExpand
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Homocysteine and oxidative stress in Egyptian children with Down syndrome.
OBJECTIVE To assess homocysteine, folic acid and vitamin B12, trace element levels and oxidant/antioxidant status in Down syndrome (DS) mothers and children. DESIGN AND METHODS 42 mothers withExpand
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Significance of vascular endothelial growth factor, interleukin-18 and nitric oxide in patients with breast cancer: correlation with carbohydrate antigen 15.3
The aim of this study was to determine serum concentrations of angiogenic factors including vascular endothelial growth factor (VEGF), interleukin 18 (IL-18) and nitric oxide (NO) in patients withExpand
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Evaluation of the potential toxicity of dibromoacetonitrile-induced apoptosis and tumor-initiating activity in rat liver.
Dibromoacetonitrile (DBAN) is water disinfectant by-product. Its broad-spectrum toxicity in different test systems in vivo and in vitro has been reported. However, there is a scanty of informationExpand
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New Biomarkers as Prognostic Factors for Cardiovascular Complications in Type 2 Diabetic Patients
This study was initiated to explore some novel biomarkers like pro-inflammatory markers (chemerin and visfatin) and anti-inflammatory marker (omentin-1) as prognostic factors for cardiovascularExpand
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Cardioprotective activity of melatonin and its novel synthesized derivatives on doxorubicin-induced cardiotoxicity.
This study aimed at evaluation of melatonin and some of its novel synthesized derivatives 3, 4, 9 and 10b as cardioprotective agents against doxorubicin-induced acute cardiac toxicity in rats. Also,Expand
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Neuroprotective effects of dehydroepiandrosterone (DHEA) in rat model of Alzheimer's disease.
The current study was undertaken to elucidate a possible neuroprotective role of dehydroepiandrosterone (DHEA) against the development of Alzheimer's disease in experimental rat model. Alzheimer'sExpand
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Molecular mechanisms of the anti-obesity potential effect of Moringa oleifera in the experimental model
Abstract Objective To elucidate the molecular mechanisms of the potent anti-obesity effect of Moringa oleifera Lam. ( M. oleifera ) ethanolic extract and to clarify the link between these mechanismsExpand
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Synthesis of novel steroidal curcumin derivatives as anti-Alzheimer’s disease candidates: Evidences-based on in vivo study
Alzheimer's disease (AD) is a complex disease in which a single monofunctional 'targeted' drug is uneffective for management. Hybrid drugs that impact multiple targets simultaneously are better atExpand
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Possible mechanisms for N-acetyl cysteine and taurine in ameliorating acute renal failure induced by cisplatin in rats
Context: Cisplatin (CP), a broadly used anticancer drug, is widely known to induce acute renal failure as a result of renal tubular injury. Objective: In this study, the effect of N-acetyl cysteineExpand
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