• Publications
  • Influence
ANALYSIS OF VIRAL DNA, PROTEIN AND ENVELOPE DAMAGE AFTER METHYLENE BLUE, PHTHALOCYANINE DERIVATIVE OR MEROCYANINE 540 PHOTOSENSITIZATION
Abstract— Although numerous photosensitizers have been used experimentally to decontaminate viruses in cellular blood components, little is known about their mechanisms of photoinactivation. UsingExpand
  • 58
  • 2
Pyrimidine Dimer Formation and Oxidative Damage in M13 Bacteriophage Inactivation by Ultraviolet C Irradiation¶
Abstract The mechanism by which UV-C irradiation inactivates M13 bacteriophage was studied by analyzing the M13 genome using agarose gel electrophoresis and South-Western blotting for pyrimidineExpand
  • 14
  • 2
Photoinactivation of Virus Infectivity by Hypocrellin A
Abstract— We investigated the photoinactivation of virus infectivity by hypocrellin A and its mechanism. The titers of vesicular stomatitis virus (VSV) and human immunodeficiency virus type 1Expand
  • 60
  • 1
Effects of Hemoglobin Vesicles, a Liposomal Artificial Oxygen Carrier, on Hematological Responses, Complement and Anaphylactic Reactions in Rats
Hemoglobin vesicle (HbV), a liposomal oxygen carrier containing human hemoglobin, was intravenously infused into rats. After the infusion of saline, the HbV or empty vesicle (EV), numbers of redExpand
  • 27
  • 1
Potential Involvement of Both Type I and Type II Mechanisms in M13 Virus Inactivation by Methylene Blue Photosensitization
We have investigated the mechanism of virus photoinactivation with methylene blue (MB) by conducting deuterium oxide (D2O), azide ion (N3‐) and oxygen‐dependent, studies. Inactivation of M13Expand
  • 25
  • 1
Leakage of potassium from red blood cells following gamma ray irradiation in the presence of dipyridamole, trolox, human plasma or mannitol.
Transfusion-associated graft-versus-host disease (TA-GVHD) is a fatal complication of blood transfusion resulting from the contamination of blood products by leukocytes. In order to prevent thisExpand
  • 30
  • 1
  • PDF
Hypotensive reactions with a white cell‐reduction filter: activation of kallikrein‐kinin cascade in a patient
blood pressure changes have been recorded during these transfusions. We believe the above two cases are consistent with the acute generation of bradykinin during filtration of the RBC component.Expand
  • 32
  • 1
Involvement of reactive oxygen species in hemoglobin oxidation and virus inactivation by 1,9-dimethylmethylene blue phototreatment.
The participation of reactive oxygen species (ROS) in virus inactivation by 1,9-dimethylmethylene blue (DMMB) phototreatment in stroma-free hemoglobin (SFH) was investigated with the use ofExpand
  • 7
  • 1
Virus Photoinactivation in Stroma-free Hemoglobin with Methylene Blue or 1,9-dimethylmethylene Blue
Abstract Photoinactivation of vesicular stomatitis virus (VSV) in stroma-free hemoglobin (SFH) was carried out using methylene blue (MB) or 1,9-dimethylmethylene blue (DMMB). The VSV was moreExpand
  • 6
  • 1
Development of analytical methods to evaluate SFH.
For the determination of stroma content in SFH, two analytical methods were developed, the HPLC-UV for phospholipids and the enzyme immunoassay for blood group antigen. These analytical methods wereExpand
  • 2
...
1
2
3
4
5
...