H. Widjaja

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New drugs are needed for preventing drug-resistant Plasmodium falciparum malaria. The prophylactic efficacy of azithromycin against P. falciparum in malaria-immune Kenyans was 83%. We conducted a double-blind, placebo-controlled trial to determine the prophylactic efficacy of azithromycin against multidrug-resistant P. falciparum malaria and(More)
Program visualisation focuses on the graphical representation of an executing program and its data. The information is presented in a form designed to enhance both the understanding and productivity of the programmer through the eecient use of the human visual system. The programmer is able to observe patterns of behaviour within the executing code and(More)
Combination therapy is one method of overcoming the global challenge of drug-resistant Plasmodium falciparum malaria. We conducted a hospital-based 28-day in vivo test comparing chloroquine/doxycycline to chloroquine or doxycycline alone for treating P. falciparum and Plasmodium vivax malaria in Irian Jaya, Indonesia. Eighty-nine patients with uncomplicated(More)
BACKGROUND There are limited data on the evolution of the leukocyte and platelet counts in malaria patients. METHODS In a clinical trial of chloroquine vs. chloroquine plus doxycycline vs. doxycycline alone against Plasmodium vivax (n = 64) or Plasmodium falciparum (n = 98) malaria, the total white cell (WCC) and platelet (PLT) counts were measured on(More)
Haemoglobin (Hb) recovers slowly in malaria and may be influenced by naturally acquired immunity. Hb recovery was compared in malaria immune, indigenous Papuan and non-Papuan adults with limited malaria exposure. Hb concentrations were measured on Days (D) 0, 3, 7, and 28 in 57 Papuans and 105 non-Papuans treated with chloroquine, doxycycline or both drugs(More)
Immune suppression resulting from prolonged chemoprophylaxis and potential drug-vaccine interaction were investigated within the context of a randomized placebo-controlled trial that compared daily primaquine or weekly chloroquine administration for malaria prevention. After 11 months of prophylaxis, adult male subjects received a tetanus-diphtheria (Td)(More)
The use of program visualisation for understanding and ne-tuning task-parallel object-oriented programs is desirable. One reason is that such programs typically involve complex interactions between the program entities. Combined with other tools, program visualisation tools can make understanding and ne-tuning of such programs easier. For maximum beneet,(More)
The use of program visualisation for understanding and ne-tuning task-parallel object-oriented programs is desirable. One reason is that such programs typically involve complex interactions between the program entities. Combined with other tools, program visualisation tools can make understanding and ne-tuning of such programs easier. For maximum beneet,(More)