H-W Bao

Learn More
Transcatheter arterial chemoembolization (TACE) with iodized oil and anticancer agents is widely used for hepatocellular carcinoma (HCC) treatment. To assess C-arm angiographic computed tomography (CCT) for detecting iodized oil retention during TACE, CCT images were obtained of 40 tumours (24 HCC patients). The primary CCT images showed complete iodized(More)
The Tibet chicken lives in high altitude and has adapted itself well to hypoxia. The Silky chicken is a lowland chicken from Jiangxi province of China. The objective of the present study was to investigate whether there were any differences in brain mitochondrial respiratory function between Tibet chicken and Silky chicken embryos incubated in a normoxic(More)
Oxygen is one of the critical determinants for normal embryonic and fetal development. In avian embryos, lack of oxygen will lead to high fetal mortality, heteroplasia, and cardiovascular dysfunction. Tibetan chicken is a breed native to Tibet that could survive and keep higher hatchability regardless of negative effects of hypoxia. Generally, adaptive(More)
The problem of hypoxia adaptation in high altitudes is an unsolved brainteaser in the field of the life sciences. As one of the best chicken breeds with adaptability to highland environment, the Tibet chicken, is genetically different from lowland chicken breeds. It is well known that hypoxia has significant impact on growth by inducing the expression of(More)
NADH dehydrogenase (complex I) couples the oxidation of NADH for the reduction of ubiquinone with the generation of a proton gradient that can be used for the synthesis of ATP. We have found a missense mutation in the MT-ND5 subunit of NADH dehydrogenase in the Tibet chicken breed. In the present study, the mitochondrial respiratory control ratio (RCR) and(More)
The Tibet chicken originates from the Qinghai-Tibet Plateau and has adapted well to hypoxia, whereas the Silky chicken is a lowland chicken breed from an area with an altitude of 750 m. The objective of the present study was to investigate whether differences exist in glutathione and related metabolism between the Tibet chicken and the Silky chicken when(More)
NADH dehydrogenase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone with pumping protons across the mitochondrial inner membrane and produces reactive oxygen species as a major source in mitochondria. A missense mutation in the mitochondrially encoded NADH dehydrogenase 2 (MT-ND2) gene, which could produce a change in the protein's(More)
  • 1