H. Urbach

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PURPOSE Temporal lobe epilepsy with antibodies (abs) against the glutamic acid decarboxylase 65 isoform (GAD-TLE) is known as an immune-mediated neurological syndrome. Here we evaluate the therapy response to various immunotherapies and epilepsy surgery in this syndrome. METHOD All patients with GAD-TLE and follow-up data and stored serum and CSF samples,(More)
We experimentally demonstrate that a femtosecond frequency comb laser can be applied as a tool for long-distance measurement in air. Our method is based on the measurement of cross correlation between individual pulses in a Michelson interferometer. From the position of the correlation functions, distances of up to 50 m have been measured. We have compared(More)
  • M. Boes, J. Bauer, H. Urbach, C.E. Elger, S. Frank, M. Baron +3 others
  • 2009
This case concerns a 17-year-old boy, who was given the diagnosis of Alpers syndrome only postmortem when a homozygous 1399G-->A (A467T) mutation was found in the linker-region of POLG1. Serial muscle and liver biopsies as well as brain MRI scans in our patient ranging from early childhood to postmortem analyses showed that (i) routine diagnostic procedures(More)
We experimentally demonstrate long distance measurements with a femtosecond frequency comb laser using dispersive interferometry. The distance is derived from the unwrapped spectral phase of the dispersed interferometer output and the repetition frequency of the laser. For an interferometer length of 50 m this approach has been compared to an independent(More)
We use finite-difference time-domain (FDTD) simulations to demonstrate enhanced infrared absorption in a photodetector covered with a microstructured metal film consisting of a metal-plasmon grating collec-tor/concentrator and sub-wavelength detector well; for circular gratings we use radial FDTD, and for linear gratings we use two-dimensional FDTD. We(More)
We apply a phase retrieval algorithm to the intensity pattern of a Hartmann wavefront sensor to measure with enhanced accuracy the phase structure of a Hartmann hole array. It is shown that the rms wavefront error achieved by phase reconstruction is one order of magnitude smaller than the one obtained from a typical centroid algorithm. Experimental results(More)
Dr. F. Bociort has provided substantial guidance and support in the preparation of this thesis. 1.1. Historical overview of imaging systems development Image formation is the main application of traditional optical systems such as loupe, telescope, microscope, camera, etc. In fact, lenses form images even if this is not their intended purpose. The history(More)
We present a concealing method in which an anti-point spread function (APSF) is generated using binary optics, which produces a large-scale dark area in the focal region that can hide any object located within it. This result is achieved by generating two identical PSFs of opposite signs, one consisting of positive electromagnetic waves from the zero-phase(More)
In a longitudinal mouse study we evaluated whether diffusion tensor imaging (DTI) can monitor microstructural changes after administration of the neuromodulating drug EPO and whether erythropoietin (EPO) has an effect on cognitive performance. Twelve mice (2 groups with 6 mice each) were scanned in a 7T Bruker Biospin animal scanner with a highly resolved(More)