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Mice lacking the voltage-gated potassium channel alpha subunit, K(V)1.1, display frequent spontaneous seizures throughout adult life. In hippocampal slices from homozygous K(V)1.1 null animals, intrinsic passive properties of CA3 pyramidal cells are normal. However, antidromic action potentials are recruited at lower thresholds in K(V)1.1 null slices.(More)
Voltage-gated K+ channels are localized to juxtaparanodal regions of myelinated axons. To begin to understand the role of normal compact myelin in this localization, we examined mKv1.1 and mKv1.2 expression in the dysmyelinating mouse mutants shiverer and Trembler. In neonatal wild-type and shiverer mice, the focal localization of both proteins in axon(More)
Computing motion on the basis of the time-varying image intensity is a difficult problem for both artificial and biological vision systems. We show how gradient models, a well known class of motion algorithms, can be implemented within the magnocellular pathway of the primate's visual system. Our cooperative algorithm computes optical flow in two steps. In(More)
Computing motion on the basis of the time-varying image intensity is a difficult problem for both artificial and biological vision systems. We will show how one well-known gradient-based computer algorithm for estimating visual motion can be implemented within the primate's visual system. This relaxation algorithm computes the optical flow field by(More)
We demonstrate a multiscale adaptive network model of motion computation in primate area MT. The model consists of two stages: (l) local velocities are measured across multiple spatio-temporal channels, and (2) the optical flow field is computed by a network of direction-selective neurons at multiple spatial resolutions. This model embeds the computational(More)
Generations of efficient blue light at 447 nm and red light at 671 nm were achieved by frequency doubling and tripling of a diode-pumped, Q-switched 1342 nm Nd:YVO 4 laser with a periodically poled LiTaO 3 ͑PPLT͒. The blue light at 447 nm was generated by sum-frequency mixing of the fundamental at 1342 nm with the generated second harmonic at 671 nm. The(More)
A neural network model of motion-field computation in the visual system of primates is proposed. The model assumes that local velocities are computed first in the primary visual cortex using information available from the sustained and transient pathways originating in the retina. A variation of the optical flow of algorithm B.K.P. Horn and B.G. Schunck(More)
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