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Bioinformatic analysis of the prognostic value of ZNF860 in recurrence-free survival and its potential regulative network in gastric cancer.
ZNF860 RNA upregulation was an independent prognostic indicator in terms of RFS in stage I/II GC and DNA CNAs and methylation alterations might collaboratively regulate ZNF860 expression.
Prognostic Value of the TP53 Mutation Location in Metastatic Breast Cancer as Detected by Next-Generation Sequencing
TP53-mutated MBC patients had a significantly worse outcome than TP53 wild-type patients especially those in HR+/HER2– and TNBC cohorts, and TP53 mutations were also associated with endocrine resistance.