H.-P. Schlemmer

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PURPOSE To flesh out the ESUR guidelines for the standardized interpretation of multiparametric magnetic resonance imaging (mMRI) for the detection of prostate cancer and to present a graphic reporting scheme for improved communication of findings to urologists. MATERIALS AND METHODS The ESUR has recently published a structured reporting system for mMRI(More)
We describe the optimal high-level postprocessing of single-voxel (1)H magnetic resonance spectra and assess the benefits and limitations of automated methods as diagnostic aids in the detection of recurrent brain tumor. In a previous clinical study, 90 long-echo-time single-voxel spectra were obtained from 52 patients and classified during follow-up(More)
A recent report of the feasibility of simultaneous PET/MR imaging of the healthy human brain has sparked excitement in the field of neuroimaging because of its potential influence and utility in clinical neuroscience research. The aim of this communication is to discuss the benefits and current drawbacks of the hybrid imaging system and to highlight some(More)
Radiotherapy could be considerably improved by the recent development of three-dimensional intensity-modulated radiation therapy. This technique allows the concept of so-called dose painting or adaptive dose distribution to be implemented with improved aligning of the dose distribution along the complex geometric arrangements of the tumour and the surround(More)
AIM Supplementary functional information can contribute to assess response in targeted therapies. The aim of this study was to evaluate semi-automatic RECIST plus iodine uptake (IU) determination in melanoma metastases under BRAF inhibitor (vemurafenib) therapy using dual-energy computed tomography (DECT). METHODS Nine patients with stage IV melanoma(More)
BACKGROUND AND PURPOSE Dynamic contrast-enhanced MR imaging can provide in vivo assessment of the microvasculature in intracranial tumors. The aim of the present study was to evaluate the diagnostic performance of dynamic contrast-enhanced MR imaging derived vascular permeability parameters, including the volume transfer constant, the volume of(More)
Transverse relaxation rates for Carr-Purcell-Meiboom-Gill (CPMG) sequences increase with inter-echo time in presence of microscopic magnetic field inhomogeneities due to nuclear spin diffusion. For a weak field approximation that includes diffusion effects, the CPMG relaxation rate shift for proton diffusion around capillaries in muscle tissue can be(More)
Aim Multiparametric MRI (mpMRI) and MRI-targeted fusion-biopsy (TB) detect significant prostate cancer (PC) more accurately than conventional biopsies alone. The aim of this study was to evaluate the detection accuracy by mpMRI and TB on radical prostatectomy (RP) specimen. Methods We selected 120 consecutive patients who underwent transperineal(More)
Aim Comparison of the sensitivities in lesion detection of 18 F-FDG-positron emission tomography (PET) and diffusion weighted imaging (DWI) in multiple myeloma patients. Methods 24 primary and pre-treated patients diagnosed with multiple myeloma according to the International Myeloma Working Group criteria were examined by 18 F-FDG PET/CT and whole-body MRI(More)
Learning objectives • Dual-energy CT (DECT) can amply contribute to a more efficient workflow in oncologic imaging. • DECT has the potential to reduce the radiation dose and to replace classical dual-phase protocols. • DECT improves oncologic imaging with improved tumour detection and opens up avenues for tissue differentiation and characterisation. • DECT(More)