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The mortality of diabetic patients with autonomic neuropathy (DAN) is higher than that in those without autonomic neuropathy (DM). To test the hypothesis that this may be due to respiratory rather than cardiac dysfunction, we evaluated ventilatory responses to isocapnic-hypoxic and hyperoxic-hypercapnic conditions in 14 diabetic patients (8 DAN and 6 DM)(More)
We compared 11 patients with upper airway obstruction (obstruction at or proximal to the carina) to 22 patients with chronic obstructive pulmonary disease and to 15 normal subjects utilizing spirometry, lung volumes, airway resistance, maximal voluntary ventilation, single-breath diffusion capacity, and maximal inspiratory and expiratory flow-volume loops.(More)
Two cases of asymptomatic cryptococcal meningitis are described. The disease was diagnosed only after Cryptococcus neoformans was cultured from lung tissue and urine. These cases represent 2 of 11 meningitis cases seen in a 10-yr period at this hospital. Of 11 cases of extraneural cryptococcosis, 6 had lumbar punctures and these 2 had positive culture(More)
Many patients with chronic obstructive pulmonary disease (COPD) receiving supplemental oxygen state that this treatment makes them less short of breath at rest. We postulated that this phenomenon may be related to improved arterial oxygenation, reduced ventilation, or stimulation of nasal receptors caused by the flow of gas. Eight patients who reported this(More)
Ribavirin aerosol is effective in treating respiratory syncytial virus and influenzal infections in children and young adults. It has not been studied in elderly patients. We evaluated the safety of ribavirin aerosol in eight elderly volunteers at high risk for influenza. Their mean age was 64 years; seven subjects had chronic obstructive pulmonary disease(More)
  • H P Liss
  • 1986
In the 1950s, researchers devised the best methods of ventilation. In the 1960s, a method of maintaining circulation and ventilation simultaneously was introduced. In the 1970s, refinements of the understanding of the mechanisms of blood flow during CPR were defined and were accompanied by an aggressive research effort to identify means to improve brain(More)