H N Sanders

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We examined the effects of administration of two hypothalamic neurohormones, TRH and GnRH, for 3 days in five anemic male dialysis patients and five age-matched normal male volunteers. Patients on chronic hemodialysis have abnormal hypothalamo-hypophyseal thyroid and gonadal functions, including blunted TSH response to TRH, hyperprolactinemia, elevated(More)
Endocrine abnormalities in chronic hemodialysis patients are in part corrected by control of anemia with recombinant human erythropoietin (rHu-EPO). We further examined the role of rHu-EPO in select hormonal abnormalities thought to be anemia related as well as the GH-insulin-like growth factor 1 (GH-IGF-1) axis that is abnormal in hemodialysis patients. We(More)
Eating is considered a pleasant and enjoyable part of everyday routine for most people. But for many elderly people with disabilities, it can become an almost impossible task. As a result, they become a "dependent eater." There are many factors that have a profound effect on the entire course of the feeding process. The caregiver must consider these factors(More)
OBJECTIVE To investigate the effects of the presence/absence of potassium in the dialysate on total body potassium content in stable hemodialysis patients. DESIGN Randomized selection. SETTING Outpatient chronic hemodialysis unit at the James A. Haley VA Hospital in Tampa, Florida. PATIENTS Six adult hemodialysis patients (mean age 48 +/- 11.61 years,(More)
The treatment of anemia in patients with renal failure has been dramatically changed with the development of recombinant human erythropoietin (r-HuEPO). This review discusses the pathogenesis of the anemia renal failure and the biology of erythropoietin. Causes of poor response to r-HuEPO therapy are outlined, and the importance of adequate available iron(More)
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