H. N. Rabes

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OVERALL AND GENE-SPECIFIC REPAIR OF DNA O-ALKYLATION PRODUCTS: RELEVANCE FOR MUTAGENESlS AND CARCINOGENIC RISK J. Engelbergs, J. Thoma~e and M.F. Rajewsky Gene-specific DNA damage and repair are important determinants in the relative frequency of mutations and malignant conversion in mammalian cells exposed to DNA-reactive agents. We have developed a(More)
Single cell DNA cytophotometry of ATPase-deficient putative preneoplastic foci in rat liver was performed. These foci were induced by treatment of male Wistar AF/Han rats with a single dose of N-methyl-N-nitrosourea (25 mg/kg or 50 mg/kg) administered 25 hr after partial hepatectomy and I hr after hydroxyurea infusion from 14 to 24 hr after operation. By(More)
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