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In animals, chronic stress leads to the development of depression-like behavior and decreases neurogenesis and blood vessel density in hippocampus, whereas antidepressants increase adult neurogenesis in hippocampus. Regular exercise training also has antidepressant action and increases hippocampal neurogenesis; however, whether exercise-induced(More)
OBJECTIVE To quantify velocity dependent and position related properties of increased muscle tone measured during a constant velocity stretch. METHODS Elbow flexors were vertically stretched under four different velocities (40, 80, 120, and 160 degrees /s) through a 75 degrees range of motion in 12 patients with hemiparesis, 16 with parkinsonism, and 12(More)
The suprachiasmatic nucleus (SCN) contains a circadian clock that maintains its time-generating and phase-modulating capacities in vitro. Previous studies report clear differences in the ability of serotonergic stimuli to phase-shift the SCN clock when applied directly to the SCN either in vivo or in vitro: while mice and rat circadian clocks are readily(More)
  • J-G Song, S-M Jeong, I-G Jun, H-M Lee, G-S Hwang
  • 2014
BACKGROUND Early detection of coagulopathy is important to prevent bleeding during liver transplantation (LT). Rotation thromboelastometry (ROTEM(®)) provides the earliest parameter of clot amplitudes at 5 min (A5). We evaluated whether A5 correlates with platelet count (PLT) and fibrinogen concentration (Fib) and can predict thrombocytopenia and(More)
  • E-H Lee, H-M Lee, +5 authors I-C Choi
  • 2011
BACKGROUND Lidocaine has been demonstrated to exert cardioprotective effects against myocardial ischaemia and reperfusion injury. We evaluated whether a continuous i.v. infusion of lidocaine reduced myocardial injury in patients undergoing off-pump coronary artery bypass graft surgery (OPCAB). METHODS In this randomized, double-blinded trial, 99 patients(More)
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