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A time-course study on production of vasopressin neurons (VP-neurons) in the mouse hypothalamus was carried out by application of [3H]thymidine autoradiography and PAP-immunocytochemistry simultaneously on the same tissue sections. In the paraventricular nucleus (PVN) and the supraoptic nucleus (SON), heavily [3H]thymidine-labeled VP-neurons were detected(More)
Cefotiam (CTM) is a new synthetic cephem antibiotic developed in Japan. The results of the fundamental and clinical studies are as follows. 1. CTM showed antibacterial activity, in terms of MIC, as strong as those of cephalothin (CET) and cefazolin (CEZ) for Gram-positive cocci, and several times superior to for Gram-negative bacilli. 2. CTM serum levels(More)
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