H. J. Sutherland

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The purpose of this study was to examine attitudes toward the duration of survival in different health states. Health professionals were asked to consider hypothetical situations in which a specified period of time would be spent in a defined health state. Preferences for these different situations were assessed using two methods--a Preference Questionnaire(More)
The standard gamble, derived from decision theory, is considered a criterion method for obtaining patients' values for different health states. In this method, a rater's value for a health state is obtained by determining, in a hypothetical setting, his readiness to remain in that state or take a risky choice with different outcomes of known value.(More)
In health status index construction quantitative values for different states of health are frequently obtained by presenting written descriptions to raters whose values are elicited using one or more methods. In this study the authors examined the influence of several aspects of this measurement process upon the quantitative results obtained. They prepared(More)
We have found that the small population of cells in human marrow that are characterized by their expression of CD34 can be readily subdivided into two apparently nonoverlapping subpopulations of approximate equal size, one expressing CD45RO and one CD45R. Functional studies of these subpopulations revealed that all of the primitive erythroid colony-forming(More)
Despite the usual uniform and primitive appearance of cells derived from the leukemic clone in most patients with acute myeloid leukemia (AML), there is considerable heterogeneity among leukemic blasts, particularly with respect to their capacity to proliferate and/or self renew. We have assessed whether these differences in proliferative potential are(More)
Twenty-one patients with poor prognosis nonseminomatous germ cell tumours (six with extreme burden disease at presentation in whom partial remission had been achieved with initial induction therapy, and 15 with recurrent disease after induction therapy) were treated with high-dose chemotherapy and autologous bone marrow transplantation (BMT). The first six(More)
by the United States Government, any agency thereof or any of their contractors or subcontractors. The views and opinions expressed herein do not necessarily state or reflect those of the United States Government, any agency thereof or any of their contractors.
Robust estimation of wind turbine design loads for service lifetimes of 30 to 50 years that are based on field measurements of a few days is a challenging problem. Estimating the long-term load distribution involves the integration of conditional distributions of extreme loads over the mean wind speed and turbulence intensity distributions. However, the(More)
The theory of reasoned action, which postulates that personal attitudes and external social influences predict intentions to undertake a behavior, was used as a conceptual framework for developing a questionnaire to elicit beliefs and attitudes associated with the decision to participate in a hypothetical cancer chemotherapy trial. After completing the(More)
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