H. J. Ryser

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The combined carcinogenic effect of cadmium and dimethylnitrosamine (DMN) was examined in male Wistar rats, to test whether the previously observed synergism in mutagenicity between cadmium and 2 N-nitroso compounds would be paralleled by a synergism in carcinogenicity. In experiment 1, 50 five-month old rats received 18 mg DMN/kg i.p. followed by cadmium(More)
Cellular uptake of 3H-heparin by cultured Chinese hamster ovary cells does not follow the pattern that would be expected on the basis of binding kinetics. It is essentially non-saturable and its low pinocytotic index is consistent with fluid-phase endocytosis, while surface binding is saturable and suggests the presence of specific receptors. Most of the(More)
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